120) Low serum non-HDL-C levels may be a predictive marker associated with an increase in the incidence of ischemic stroke and possibly of cardioembolic infarction in Japanese women. |
PMID:23430886 DOI:10.1177/1010539513475649 |
2015 Asia-Pacific journal of public health |
* Serum non-high-density lipoprotein cholesterol levels and the incidence of ischemic stroke in a Japanese population: the Jichi Medical School cohort study. |
- The predictive value of serum non-high-density lipoprotein cholesterol (non-HDL-C) levels for the incidence of ischemic stroke and its subtypes has not yet been established. The present cohort study investigated their relationships in a Japanese population. The first incidence of ischemic stroke and its subtypes was documented as the primary outcome. A total of 249 ischemic stroke patients (men/women = 145/104) were identified during a follow-up period of 10.7 years among 10 760 community-dwelling subjects (men/women = 4212/6548). Cox proportional hazard model analyses revealed that when compared with the lowest tertile of non-HDL-C, multivariate-adjusted hazard ratios for the highest tertile were 0.55 (95% confidence interval = 0.32-0.95, P = .03) on ischemic stroke and 0.29 (95% confidence interval = 0.08-1.05, P = .06) on cardioembolic infarction in women. Men did not show such significant relationships. Low serum non-HDL-C levels may be a predictive marker associated with an increase in the incidence of ischemic stroke and possibly of cardioembolic infarction in Japanese women. |
(1)51 the | (16)4 significantly | (31)2 being | (46)2 less |
(2)31 a | (17)3 FIQ | (32)2 diabetes | (47)2 many |
(3)12 increased | (18)3 cancer | (33)2 different | (48)2 maternal |
(4)12 lower | (19)3 chronic | (34)2 early | (49)2 nephrolithiasis |
(5)9 higher | (20)3 more | (35)2 excessive | (50)2 normal |
(6)8 an | (21)3 other | (36)2 faster | (51)2 parenchymal |
(7)7 decreased | (22)3 perceived | (37)2 female | (52)2 physical |
(8)6 poor | (23)3 shorter | (38)2 gene | (53)2 positive |
(9)5 both | (24)3 smoking | (39)2 genetic | (54)2 reductions |
(10)5 greater | (25)3 specific | (40)2 good | (55)2 stress |
(11)4 adverse | (26)2 JS | (41)2 having | (56)2 them |
(12)4 negative | (27)2 SWD | (42)2 high | (57)2 this |
(13)4 poorer | (28)2 alterations | (43)2 implementation | (58)2 undernutrition |
(14)4 reduced | (29)2 altered | (44)2 improvements | (59)2 very |
(15)4 significant | (30)2 any | (45)2 internalizing |
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