ELIZA cgi-bash version rev. 1.91
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for associated with out of >500 occurrences
579792 occurrences (No.16 in the rank) during 5 years in the PubMed. [cache]
184) We implemented a novel multi-omic data integration method based on multilayered principal component analysis, penalized regression, and feature weight back-propagation, which enabled us to identify cellular pathways associated with RSV severity.
--- ABSTRACT ---
PMID:34962914 DOI:10.1371/journal.pcbi.1009617
2021 PLoS computational biology
* A systems genomics approach uncovers molecular associates of RSV severity.
- Respiratory syncytial virus (RSV) infection results in millions of hospitalizations and thousands of deaths each year. Variations in the adaptive and innate immune response appear to be associated with RSV severity. To investigate the host response to RSV infection in infants, we performed a systems-level study of RSV pathophysiology, incorporating high-throughput measurements of the peripheral innate and adaptive immune systems and the airway epithelium and microbiota. We implemented a novel multi-omic data integration method based on multilayered principal component analysis, penalized regression, and feature weight back-propagation, which enabled us to identify cellular pathways associated with RSV severity. In both airway and immune cells, we found an association between RSV severity and activation of pathways controlling Th17 and acute phase response signaling, as well as inhibition of B cell receptor signaling. Dysregulation of both the humoral and mucosal response to RSV may play a critical role in determining illness severity.
--- ABSTRACT END ---
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[frequency of next (right) word to associated with]
(1)42 the (17)4 risk (33)2 ICU (49)2 increasing
(2)29 a (18)4 several (34)2 PTSD (50)2 its
(3)22 increased (19)4 worse (35)2 PTSD, (51)2 levels
(4)14 an (20)3 RSV (36)2 alterations (52)2 low
(5)7 higher (21)3 acute (37)2 appropriate (53)2 multiple
(6)7 poor (22)3 both (38)2 brain (54)2 non-adherence
(7)6 asthma (23)3 differences (39)2 decreased (55)2 other
(8)6 lower (24)3 drug (40)2 diminished (56)2 poorer
(9)5 better (25)3 each (41)2 effective (57)2 rare
(10)5 more (26)3 greater (42)2 enhanced (58)2 reduced
(11)5 these (27)3 high (43)2 frailty (59)2 smaller
(12)5 various (28)3 shorter (44)2 gut (60)2 this
(13)4 altered (29)3 significant (45)2 human (61)2 treatment
(14)4 cognitive (30)3 statin (46)2 impaired (62)2 vaccine
(15)4 health (31)3 vaccination (47)2 incorporating (63)2 vaping
(16)4 improved (32)2 CKD (48)2 increases

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--- WordNet output for associated --- Overview of verb associate The verb associate has 3 senses (first 3 from tagged texts) 1. (25) associate, tie in, relate, link, colligate, link up, connect -- (make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all") 2. (3) consort, associate, affiliate, assort -- (keep company with; hang out with; "He associates with strange people"; "She affiliates with her colleagues") 3. (1) consociate, associate -- (bring or come into association or action; "The churches consociated to fight their dissolution") --- WordNet end ---