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579792 occurrences (No.16 in the rank) during 5 years in the PubMed. [no cache] 500 found

282) Tumour recurrence rates and tumour-related deaths were not associated with KIT staining patterns (P = 0278, P > 0.05), KIT (P = 0.289, P > 0.05) or KIT ligand (P = 0.106, P > 0.05) gene expression.

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PMID:23294979 DOI:10.1111/vco.12010

2015 Veterinary and comparative oncology

* The value of molecular expression of KIT and KIT ligand analysed using real-time polymerase chain reaction and immunohistochemistry as a prognostic indicator for canine cutaneous mast cell tumours.

- This study investigated the correlation between KIT gene expression determined by immunohistochemistry and real-time polymerase chain reaction (RT-PCR) and the rate of tumour recurrence and tumour-related deaths in dogs affected with mast cell tumour (MCT). Kaplan-Meier curves were constructed to compare tumour recurrence and tumour-related death between patients. The log-rank test was used to check for significant differences between curves. KIT-I, KIT-II and KIT-III staining patterns were observed in 9 (11.11%), 50 (61.73%) and 22 (27.16%) tumours, respectively. Tumour recurrence rates and tumour-related deaths were not associated with KIT staining patterns (P = 0278, P > 0.05), KIT (P = 0.289, P > 0.05) or KIT ligand (P = 0.106, P > 0.05) gene expression. Despite the lack of association between KIT staining pattern and patient survival time, the results suggest a correlation between aberrant KIT localization and increased proliferative activity of MCTs. RT-PCR seems to be a sensible method for quantitative detection of KIT gene expression in canine MCT, although expressions levels are not correlated with prognosis.

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(1)51 the	(16)4 significantly	(31)2 being	(46)2 less
(2)31 a	(17)3 FIQ	(32)2 diabetes	(47)2 many
(3)12 increased	(18)3 cancer	(33)2 different	(48)2 maternal
(4)12 lower	(19)3 chronic	(34)2 early	(49)2 nephrolithiasis
(5)9 higher	(20)3 more	(35)2 excessive	(50)2 normal
(6)8 an	(21)3 other	(36)2 faster	(51)2 parenchymal
(7)7 decreased	(22)3 perceived	(37)2 female	(52)2 physical
(8)6 poor	(23)3 shorter	(38)2 gene	(53)2 positive
(9)5 both	(24)3 smoking	(39)2 genetic	(54)2 reductions
(10)5 greater	(25)3 specific	(40)2 good	(55)2 stress
(11)4 adverse	(26)2 JS	(41)2 having	(56)2 them
(12)4 negative	(27)2 SWD	(42)2 high	(57)2 this
(13)4 poorer	(28)2 alterations	(43)2 implementation	(58)2 undernutrition
(14)4 reduced	(29)2 altered	(44)2 improvements	(59)2 very
(15)4 significant	(30)2 any	(45)2 internalizing

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--- WordNet output for associated --- Overview of verb associate The verb associate has 3 senses (first 3 from tagged texts) 1. (25) associate, tie in, relate, link, colligate, link up, connect -- (make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all") 2. (3) consort, associate, affiliate, assort -- (keep company with; hang out with; "He associates with strange people"; "She affiliates with her colleagues") 3. (1) consociate, associate -- (bring or come into association or action; "The churches consociated to fight their dissolution") --- WordNet end ---