* A Novel Cobalt(II) Coordination Complex Constructed from H2Pyri and 4,4'-Bipy: Synthesis, Characterization and Bioactivity.
- The new complex of {[Co(4,4'-Bipy)(H2O)4]·(Pyri) · 3H2O}n (4,4'-Bipy = 4,4'-bipyridyl, H2Pyri = 3,5- Pyridinedicarboxylic acid) was synthesized and characterized by IR, element analysis and X-ray single-crystal diffraction. The binding of the complex with extracted HeLa cells DNA was investigated by UV and fluorescence spectrum. Gel electrophoresis assay demonstrated the ability of the complex cleaving the extracted HC-DNA. The complex exhibited a higher cytotoxicity against tumor cells in vitro. Furthermore, the apoptotic tests indicated the complex had an apoptotic effect on HeLa cells.
Overview of noun cell
The noun cell has 7 senses (first 3 from tagged texts)
1. (71) cell -- (any small compartment; "the cells of a honeycomb")
2. (44) cell -- ((biology) the basic structural and functional unit of all organisms; they may exist
as independent units of life (as in monads) or may form colonies or tissues as in higher plants and
animals)
3. (1) cell, electric cell -- (a device that delivers an electric current as the result of a
chemical reaction)
4. cell, cadre -- (a small unit serving as part of or as the nucleus of a larger political movement)
5. cellular telephone, cellular phone, cellphone, cell, mobile phone -- (a hand-held mobile
radiotelephone for use in an area divided into small sections, each with its own short-range
transmitter/receiver)
6. cell, cubicle -- (small room in which a monk or nun lives)
7. cell, jail cell, prison cell -- (a room where a prisoner is kept)
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