ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for changes out of >500 occurrences
332920 occurrences (No.57 in the rank) during 5 years in the PubMed. [no cache] 500 found
270) Our objective was to explore the mechanism of cell-assisted adipose transplantation by using freshly isolated human stromal vascular fraction (SVF) cells and to observe the dynamic changes of the graft after transplantation.
--- ABSTRACT ---
PMID:24172865 DOI:10.3727/096368913X675133
2015 Cell transplantation
* Adipocyte regeneration after free fat transplantation: promotion by stromal vascular fraction cells.
- Our objective was to explore the mechanism of cell-assisted adipose transplantation by using freshly isolated human stromal vascular fraction (SVF) cells and to observe the dynamic changes of the graft after transplantation. The SVF was isolated from human liposuction aspirates, and 0.5 ml adipose tissue was mixed with 1 × 10(6) SVF cells or culture medium then injected to nude mice subcutaneously. At 1, 4, 7, 14, 30, 60, and 90 days after transplantation, samples were harvested for 1) general observation and retention rate; 2) whole-mount stain; 3) H&E stain; 4) immunohistochemical staining for S100, CD68, and CD34; 5) ELISA for VEGF and bFGF; 6) peroxisome proliferator-activated receptor-γ (PPARγ) fluorescence in situ hybridization. The retention rate in the experiment group was markedly higher than that in the control group. Whole-mount stain shows most of the cells in the center of the graft could not survive the ischemia until day 14. Histology showed new vessels on the surface of the graft at 3 days. However, in the control group, fewer newly formed vessels were detected until day 7. In the late stage of transplantation, gradual fibrosis was found in the graft, and the tissue was divided into a grid-like structure. A large number of round neonatal adipocytes with big nuclei in the center were found surrounding the new vessels, which were S100 and CD34 positive and CD68 negative. In the late stage of transplantation, most of the neonatal adipocytes were human PPARγ positive. Moreover, the SVF group showed a higher level of VEGF and bFGF. SVF assisting adipose transplantation could increase the retention rate of the graft through promoting adipose tissue regeneration via secretion of growth factors, promotion of angiogenesis, and increasing the density of mesenchymal stem cells.
--- ABSTRACT END ---
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--- WordNet output for changes --- Overview of noun change The noun change has 10 senses (first 7 from tagged texts) 1. (46) change, alteration, modification -- (an event that occurs when something passes from one state or phase to another; "the change was intended to increase sales"; "this storm is certainly a change for the worse"; "the neighborhood had undergone few modifications since his last visit years ago") 2. (45) change -- (a relational difference between states; especially between states before and after some event; "he attributed the change to their marriage") 3. (17) change -- (the action of changing something; "the change of government had no impact on the economy"; "his change on abortion cost him the election") 4. (13) change -- (the result of alteration or modification; "there were marked changes in the lining of the lungs"; "there had been no change in the mountains") 5. (2) change -- (the balance of money received when the amount you tender is greater than the amount due; "I paid with a twenty and pocketed the change") 6. (1) change -- (a thing that is different; "he inspected several changes before selecting one") 7. (1) change -- (a different or fresh set of clothes; "she brought a change in her overnight bag") 8. change -- (coins of small denomination regarded collectively; "he had a pocketful of change") 9. change -- (money received in return for its equivalent in a larger denomination or a different currency; "he got change for a twenty and used it to pay the taxi driver") 10. variety, change -- (a difference that is usually pleasant; "he goes to France for variety"; "it is a refreshing change to meet a woman mechanic") Overview of verb change The verb change has 10 senses (first 8 from tagged texts) 1. (57) change, alter, modify -- (cause to change; make different; cause a transformation; "The advent of the automobile may have altered the growth pattern of the city"; "The discussion has changed my thinking about the issue") 2. (54) change -- (undergo a change; become different in essence; losing one's or its original nature; "She changed completely as she grew older"; "The weather changed last night") 3. (13) change, alter, vary -- (become different in some particular way, without permanently losing one's or its former characteristics or essence; "her mood changes in accordance with the weather"; "The supermarket's selection of vegetables varies according to the season") 4. (7) switch, shift, change -- (lay aside, abandon, or leave for another; "switch to a different brand of beer"; "She switched psychiatrists"; "The car changed lanes") 5. (6) change -- (change clothes; put on different clothes; "Change before you go to the opera") 6. (5) change, exchange, commute, convert -- (exchange or replace with another, usually of the same kind or category; "Could you convert my dollars into pounds?"; "He changed his name"; "convert centimeters into inches"; "convert holdings into shares") 7. (3) exchange, change, interchange -- (give to, and receive from, one another; "Would you change places with me?"; "We have been exchanging letters for a year") 8. (3) transfer, change -- (change from one vehicle or transportation line to another; "She changed in Chicago on her way to the East coast") 9. deepen, change -- (become deeper in tone; "His voice began to change when he was 12 years old"; "Her voice deepened when she whispered the password") 10. change -- (remove or replace the coverings of; "Father had to learn how to change the baby"; "After each guest we changed the bed linens") --- WordNet end ---