168) The purposes of this preliminary study are to assess the risk of developing bisphosphonate-related osteonecrosis of the jaw (BRONJ) in a patient with osteoporosis using zoledronic acid and to report the results of a 1-year prospective clinical study regarding 5 immediately inserted implants in the anterior mandible. |
PMID:24041299 DOI:10.1563/AAID-JOI-D-13-00063 |
2015 The Journal of oral implantology |
* Immediate Implant Placement in a Patient With Osteoporosis Undergoing Bisphosphonate Therapy: 1-Year Preliminary Prospective Study. |
- The purposes of this preliminary study are to assess the risk of developing bisphosphonate-related osteonecrosis of the jaw (BRONJ) in a patient with osteoporosis using zoledronic acid and to report the results of a 1-year prospective clinical study regarding 5 immediately inserted implants in the anterior mandible. For this comparative prospective study, 24 female patients, aged ≥54 years, were chosen, all with partially edentulous mandibles. Group A consisted of 12 patients with osteoporosis taking zoledronic acid receiving a once-yearly intravenous infusion of zoledronic acid (5 mg). Control group B consisted of 12 other patients without osteoporosis and not taking drugs. In both groups, the remaining teeth were extracted before 120 implants, 3.7-mm wide and 16-mm long, were immediately installed in the interforaminal region of the mandibles. The 1-year implant survival rate was 100%. No apparent necrotic bone was observed among patients receiving zoledronic acid (group A) after implant surgery. Immediate implant osseointegration can be successful in a patient with osteoporosis using bisphosphonates, suggesting the safety of implantology as a treatment modality. |
(1)36 and | (17)5 application | (33)3 attachment | (49)2 grading |
(2)26 practice | (18)5 data | (34)3 course, | (50)2 interventions |
(3)22 trials | (19)5 efficacy | (35)3 examination, | (51)2 literature |
(4)19 trial | (20)5 features | (36)3 experience | (52)2 measures |
(5)14 research | (21)5 outcome | (37)3 information | (53)2 nurse |
(6)14 studies | (22)5 picture | (38)3 manifestations | (54)2 observations |
(7)10 use | (23)5 relevance | (39)3 significance | (55)2 point |
(8)8 parameters | (24)5 symptoms | (40)3 variables | (56)2 practice, |
(9)8 settings | (25)5 translation | (41)2 benefits | (57)2 presentation, |
(10)8 signs | (26)5 trials, | (42)2 cases | (58)2 process |
(11)8 study | (27)5 utility | (43)2 conditions | (59)2 results |
(12)7 examination | (28)4 characteristics | (44)2 context | (60)2 sample, |
(13)7 implications | (29)4 evaluation | (45)2 decision-making | (61)2 situation |
(14)7 presentation | (30)4 management | (46)2 decisions | (62)2 situations, |
(15)6 applications | (31)4 outcomes | (47)2 diagnosis | (63)2 success |
(16)6 course | (32)4 signs, | (48)2 findings | (64)2 tooth |
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