ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for clinical out of >500 occurrences
554339 occurrences (No.20 in the rank) during 5 years in the PubMed. [no cache] 500 found
31) To support validation of milk analysers in both clinical and research settings, the aim of this study is to establish and validate micromethods for precise macronutrient analysis in small volume of breast milk and conduct a feasibility study of the micromethods as a post-validation.
--- ABSTRACT ---
PMID:23782538 DOI:10.1111/mcn.12053
2015 Maternal & child nutrition
* Establishment of micromethods for macronutrient contents analysis in breast milk.
- Commercially available milk analysers were originally developed for use in the dairy industry, but they are now used to analyse macronutrient content of breast milk in clinical studies and routine care of the premature or very low birthweight (VLBW) infants. Due to the different composition of cow and breast milk, these devices need to be validated against reference methods before they can be used in daily routine. However, current reference methods require a sample volume of 30-100 mL to analyse fat, protein and lactose. It is not feasible to obtain this volume of milk for research purposes, especially from VLBW infants as lactation may be delayed or impaired and the limited volume of breast milk must be provided to the infant. To support validation of milk analysers in both clinical and research settings, the aim of this study is to establish and validate micromethods for precise macronutrient analysis in small volume of breast milk and conduct a feasibility study of the micromethods as a post-validation. Methods include a modified Mojonnier ether extraction (fat), elemental analysis (protein) and ultra-performance liquid chromatography-tandem mass spectrometry (lactose). We were able to downsize volumes required for analysis of fat, protein and lactose to 1 mL, 260 μL and 100 μL; corresponding coefficients of variation are 1.7, 1.8 and 2.3%, respectively. The presented methods allow for reliable and precise analyses of macronutrients in ≤1.5 mL of breast milk and will be used to validate milk analysers.
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[frequency of next (right) word to clinical]
(1)36 and (17)5 application (33)3 attachment (49)2 grading
(2)26 practice (18)5 data (34)3 course, (50)2 interventions
(3)22 trials (19)5 efficacy (35)3 examination, (51)2 literature
(4)19 trial (20)5 features (36)3 experience (52)2 measures
(5)14 research (21)5 outcome (37)3 information (53)2 nurse
(6)14 studies (22)5 picture (38)3 manifestations (54)2 observations
(7)10 use (23)5 relevance (39)3 significance (55)2 point
(8)8 parameters (24)5 symptoms (40)3 variables (56)2 practice,
(9)8 settings (25)5 translation (41)2 benefits (57)2 presentation,
(10)8 signs (26)5 trials, (42)2 cases (58)2 process
(11)8 study (27)5 utility (43)2 conditions (59)2 results
(12)7 examination (28)4 characteristics (44)2 context (60)2 sample,
(13)7 implications (29)4 evaluation (45)2 decision-making (61)2 situation
(14)7 presentation (30)4 management (46)2 decisions (62)2 situations,
(15)6 applications (31)4 outcomes (47)2 diagnosis (63)2 success
(16)6 course (32)4 signs, (48)2 findings (64)2 tooth

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--- WordNet output for clinical --- =>客観的な態度の, 臨床の, 臨床治療の, 臨床, 分析的な, 冷静な, 客観的な, 病院に関するものだ, 病院関係の Overview of adj clinical The adj clinical has 2 senses (first 2 from tagged texts) 1. (14) clinical -- (relating to a clinic or conducted in or as if in a clinic and depending on direct observation of patients; "clinical observation"; "clinical case study") 2. (1) clinical -- (scientifically detached; unemotional; "he spoke in the clipped clinical monotones typical of police testimony") --- WordNet end ---