ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for clinical out of >500 occurrences
554339 occurrences (No.20 in the rank) during 5 years in the PubMed. [no cache] 500 found
319) The current study demonstrated that functional connectivity had good diagnostic potential for SAD, thus providing evidence for the possible use of whole brain functional connectivity as a complementary tool in clinical diagnosis.
--- ABSTRACT ---
PMID:24072164 DOI:10.1007/s00429-013-0641-4
2015 Brain structure & function
* Multivariate classification of social anxiety disorder using whole brain functional connectivity.
- Recent research has shown that social anxiety disorder (SAD) is accompanied by abnormalities in brain functional connections. However, these findings are based on group comparisons, and, therefore, little is known about whether functional connections could be used in the diagnosis of an individual patient with SAD. Here, we explored the potential of the functional connectivity to be used for SAD diagnosis. Twenty patients with SAD and 20 healthy controls were scanned using resting-state functional magnetic resonance imaging. The whole brain was divided into 116 regions based on automated anatomical labeling atlas. The functional connectivity between each pair of regions was computed using Pearson's correlation coefficient and used as classification feature. Multivariate pattern analysis was then used to classify patients from healthy controls. The pattern classifier was designed using linear support vector machine. Experimental results showed a correct classification rate of 82.5 % (p < 0.001) with sensitivity of 85.0 % and specificity of 80.0 %, using a leave-one-out cross-validation method. It was found that the consensus connections used to distinguish SAD were largely located within or across the default mode network, visual network, sensory-motor network, affective network, and cerebellar regions. Specifically, the right orbitofrontal region exhibited the highest weight in classification. The current study demonstrated that functional connectivity had good diagnostic potential for SAD, thus providing evidence for the possible use of whole brain functional connectivity as a complementary tool in clinical diagnosis. In addition, this study confirmed previous work and described novel pathophysiological mechanisms of SAD.
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[frequency of next (right) word to clinical]
(1)36 and (17)5 application (33)3 attachment (49)2 grading
(2)26 practice (18)5 data (34)3 course, (50)2 interventions
(3)22 trials (19)5 efficacy (35)3 examination, (51)2 literature
(4)19 trial (20)5 features (36)3 experience (52)2 measures
(5)14 research (21)5 outcome (37)3 information (53)2 nurse
(6)14 studies (22)5 picture (38)3 manifestations (54)2 observations
(7)10 use (23)5 relevance (39)3 significance (55)2 point
(8)8 parameters (24)5 symptoms (40)3 variables (56)2 practice,
(9)8 settings (25)5 translation (41)2 benefits (57)2 presentation,
(10)8 signs (26)5 trials, (42)2 cases (58)2 process
(11)8 study (27)5 utility (43)2 conditions (59)2 results
(12)7 examination (28)4 characteristics (44)2 context (60)2 sample,
(13)7 implications (29)4 evaluation (45)2 decision-making (61)2 situation
(14)7 presentation (30)4 management (46)2 decisions (62)2 situations,
(15)6 applications (31)4 outcomes (47)2 diagnosis (63)2 success
(16)6 course (32)4 signs, (48)2 findings (64)2 tooth

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--- WordNet output for clinical --- =>客観的な態度の, 臨床の, 臨床治療の, 臨床, 分析的な, 冷静な, 客観的な, 病院に関するものだ, 病院関係の Overview of adj clinical The adj clinical has 2 senses (first 2 from tagged texts) 1. (14) clinical -- (relating to a clinic or conducted in or as if in a clinic and depending on direct observation of patients; "clinical observation"; "clinical case study") 2. (1) clinical -- (scientifically detached; unemotional; "he spoke in the clipped clinical monotones typical of police testimony") --- WordNet end ---