ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for different out of >500 occurrences
683276 occurrences (No.7 in the rank) during 5 years in the PubMed. [no cache] 500 found
126) Further studies are needed to elucidate the underlying molecular mechanism responsible for the different effects evoked by TRPV1 activation in MCF-7 and CF.41 cells.
--- ABSTRACT ---
PMID:23510405 DOI:10.1111/vco.12028
2015 Veterinary and comparative oncology
* Expression and functionality of TRPV1 receptor in human MCF-7 and canine CF.41 cells.
- As canine mammary tumours (CMT) and human breast cancer share clinical and prognostic features, the former have been proposed as a model to study carcinogenesis and improved therapeutic treatment in human breast cancer. In recent years, it has been shown that transient receptor potential vanilloid 1 (TRPV1) is expressed in different neoplastic tissues and its activation has been associated with regulation of cancer growth and progression. The aim of the present research was to demonstrate the presence of TRPV1 in human and canine mammary cancer cells, MCF-7 and CF.41, respectively, and to study the role of TRPV1 in regulating cell proliferation. The images obtained by Western blot showed a signal at 100 kDa corresponding to the molecular weight of TRPV1 receptor. All tested TRPV1 agonists and antagonists caused a significant decrease (P < 0.05) of cell growth rate in MCF-7 cells. By contrast, in CF.41 cells capsaicin and capsazepine induced a significant increase (P < 0.05) in cell proliferation, whereas resiniferatoxin (RTX) and 5-iodo-resiniferatoxin (5-I-RTX) had no influence on CF.41 cell proliferation. Further studies are needed to elucidate the underlying molecular mechanism responsible for the different effects evoked by TRPV1 activation in MCF-7 and CF.41 cells.
--- ABSTRACT END ---
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(1)21 from (18)3 amounts (35)2 compared (52)2 origins
(2)15 types (19)3 aspects (36)2 dietary (53)2 output
(3)10 between (20)3 cell (37)2 diseases (54)2 pHs
(4)9 doses (21)3 degrees (38)2 dosing (55)2 patterns
(5)7 concentrations (22)3 effects (39)2 ethnic (56)2 perspectives
(6)6 time (23)3 for (40)2 flow (57)2 protocols
(7)5 in (24)3 health (41)2 frequencies (58)2 range
(8)5 levels (25)3 mechanisms (42)2 gene (59)2 regions
(9)4 *null* (26)3 parts (43)2 genes (60)2 scenarios
(10)4 areas (27)3 roles (44)2 genetic (61)2 sensory
(11)4 combinations (28)3 species (45)2 human (62)2 surface
(12)4 components (29)3 ways (46)2 indicators (63)2 taxa
(13)4 groups (30)2 abutments (47)2 internal-cone (64)2 than
(14)4 methods (31)2 and (48)2 laser (65)2 therapeutic
(15)4 stages (32)2 approaches (49)2 masking (66)2 tissues
(16)4 tilt (33)2 bleaching (50)2 materials (67)2 versions
(17)3 adhesive (34)2 changes (51)2 molecular (68)2 views

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--- WordNet output for different --- =>いろいろな, 違った, 異なった, 様々の, 種々の, 異なる, 変わった Overview of adj different The adj different has 5 senses (first 4 from tagged texts) 1. (88) different -- (unlike in nature or quality or form or degree; "took different approaches to the problem"; "came to a different conclusion"; "different parts of the country"; "on different sides of the issue"; "this meeting was different from the earlier one") 2. (41) different -- (distinctly separate from the first; "that's another (or different) issue altogether") 3. (2) different -- (differing from all others; not ordinary; "advertising that strives continually to be different"; "this new music is certainly different but I don't really like it") 4. (1) unlike, dissimilar, different -- (marked by dissimilarity; "for twins they are very unlike"; "people are profoundly different") 5. different -- (distinct or separate; "each interviewed different members of the community") --- WordNet end ---