ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for disease out of >500 occurrences
422715 occurrences (No.39 in the rank) during 5 years in the PubMed. [cache]
18) Chronic venous ulceration (CVU) is the major cause of chronic wounds of lower extremities, and is a part of the complex of chronic venous disease.
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PMID:23418772 DOI:10.1111/iwj.12042
2015 International wound journal
* Hyperhomocysteinaemia and chronic venous ulcers.
- Chronic venous ulceration (CVU) is the major cause of chronic wounds of lower extremities, and is a part of the complex of chronic venous disease. Previous studies have hypothesised that several thrombophilic factors, such as hyperhomocysteinaemia (HHcy), may be associated with chronic venous ulcers. In this study, we evaluated the prevalence of HHcy in patients with venous leg ulcers and the effect of folic acid therapy on wound healing. Eighty-seven patients with venous leg ulcers were enrolled in this study to calculate the prevalence of HHcy in this population. All patients underwent basic treatment for venous ulcer (compression therapy ± surgical procedures). Patients with HHcy (group A) received basic treatment and administered folic acid (1·2 mg/day for 12 months) and patients without HHcy (group B) received only basic treatment. Healing was assessed by means of computerised planimetry analysis. The prevalence of HHcy among patients with chronic venous ulcer enrolled in this study was 62·06%. Healing rate was significantly higher (P < 0·05) in group A patients (78·75%) compared with group B patients (63·33%). This study suggests a close association, statistically significant, between HHcy and CVU. Homocysteine-lowering therapy with folic acid seems to expedite wound healing. Despite these aspects, the exact molecular mechanisms between homocysteine and CVU have not been clearly defined and further studies are needed.
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(1)100 *null* (17)4 (PD) (33)3 to (49)2 condition,
(2)39 and (18)4 activity (34)2 (CHD) (50)2 development
(3)16 is (19)4 outcome (35)2 (COPD) (51)2 interval
(4)13 in (20)4 severity, (36)2 (CVD), (52)2 many
(5)12 of (21)4 the (37)2 (GERD) (53)2 multi-sectoral
(6)9 (FMD) (22)4 who (38)2 (LSD) (54)2 on
(7)8 risk (23)3 (CAD) (39)2 (SC) (55)2 onset
(8)7 severity (24)3 compared (40)2 Control (56)2 onset,
(9)6 progression (25)3 control (41)2 activity, (57)2 outbreaks
(10)6 that (26)3 course (42)2 are (58)2 patterns
(11)6 was (27)3 free (43)2 as (59)2 phobia
(12)5 (CVD) (28)3 has (44)2 associated (60)2 prevention
(13)5 or (29)3 management (45)2 burden (61)2 processes
(14)5 state (30)3 may (46)2 by (62)2 progression,
(15)4 (AD) (31)3 patients (47)2 can (63)2 surveillance
(16)4 (HD) (32)3 states (48)2 characterized (64)2 usually

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--- WordNet output for disease --- =>病気, 病弊, 精神の退廃 Overview of noun disease The noun disease has 1 sense (first 1 from tagged texts) 1. (26) disease -- (an impairment of health or a condition of abnormal functioning) --- WordNet end ---