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- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for due out of >500 occurrences
324863 occurrences (No.63 in the rank) during 5 years in the PubMed. [cache]
15) Due to its small size, it is easily made sterile by covering it with any sterile plastic sheet.
--- ABSTRACT ---
PMID:24354756 DOI:10.7785/tcrt.2012.500400
2015 Technology in cancer research & treatment
* Small portable interchangeable imager of fluorescence for fluorescence guided surgery and research.
- Fluorescence guided surgery (FGS) is a developing field of surgical and oncologic research. Practically, FGS has shown useful applications in urologic surgery, benign biliary surgery, colorectal cancer liver metastasis resection, and ovarian cancer debulking. Most notably in in cancer surgery, FGS allows for the clear delineation of cancerous tissue from benign tissue. FGS requires the utilization of a fluorescent contrast agent and an intraoperative fluorescence imaging device (IFID). Currently available IFIDs are expensive, unable to work with multiple fluorophores, and can be cumbersome. This study aims to describe the development and utility of a small, cost-efficient, and interchangeable IFID made from commercially available components. Extensive research was done to design and construct a light-weight, portable, and cost-effective IFID. We researched the capabilities, size, and cost of several camera types and eventually decided on a near-infrared (NIR) charged couple device (CCD) camera for its overall profile. The small portable interchangeable imager of fluorescence (SPIIF) is a "scout" IFID system for FGS. The main components of the SPIIF are a NIR CCD camera with an articulating light filter. These components and a LED light source with an attached heat sink are mounted on a small metal platform. The system is connected to a laptop by a USB 2.0 cable. Pixielink © software on the laptop runs the system by controlling exposure time, gain, and image capture. After developing the system, we evaluated its utility as an IFID. The system weighs less than two pounds and can cover a large area. Due to its small size, it is easily made sterile by covering it with any sterile plastic sheet. To determine the system's ability to detect fluorescent signal, we used the SPIIF to detect indocyanine green under ex and in-vivo conditions and fluorescein under ex-vivo conditions. We found the SPIIF was able to detect both ICG and fluorescein under different depths of a semi-opaque colloid. Second, we found that a concentration as low as 0.5 g/ml of indocyanine green dissolved in plasma was detectable. Lastly, in a murine and human cancer model, the SPIIF was able to detect indocyanine green signal within tumors and generate a signal-to-background ratio (SBR) of 3.75. This study shows that a low-cost IFID can be made from commercially available parts. Second, this IFID is capable of in and ex-vivo detection of multiple fluorophores without sacrificing its small size or favorable ergonomics.
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--- WordNet output for due --- =>1.予定の, 支払期日がきて, 当然支払われるべき, 2.支払[提出]期日, 満期日, 会費 Overview of noun due The noun due has 2 senses (first 1 from tagged texts) 1. (4) due -- (that which is deserved or owed; "give the devil his due") 2. due -- (a payment that is due (e.g., as the price of membership); "the society dropped him for non-payment of dues") Overview of adj due The adj due has 4 senses (first 2 from tagged texts) 1. (6) due -- (owed and payable immediately or on demand; "payment is due") 2. (1) due -- (scheduled to arrive; "the train is due in 15 minutes") 3. due -- (suitable to or expected in the circumstances; "all due respect"; "due cause to honor them"; "a long due promotion"; "in due course"; "due esteem"; "exercising due care") 4. ascribable, due, imputable, referable -- (capable of being assigned or credited to; "punctuation errors ascribable to careless proofreading"; "the cancellation of the concert was due to the rain"; "the oversight was not imputable to him") Overview of adv due The adv due has 1 sense (no senses from tagged texts) 1. due -- (directly or exactly; straight; "went due North") --- WordNet end ---