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319715 occurrences (No.67 in the rank) during 5 years in the PubMed. [cache]
193) Simultaneous activation of reward networks, cognitive control networks and the DMN in alcohol-dependent women suggests that over-endorsement of high-risk drinking decisions by alcohol-dependent women may be due to a problem with switching between different neural networks.
--- ABSTRACT ---
PMID:24373127 DOI:10.1111/adb.12121
2015 Addiction biology
* Neural mechanisms of high-risk decisions-to-drink in alcohol-dependent women.
- A hallmark of alcohol dependence (AD) is continually drinking despite the risk of negative consequences. Currently, it is not known if the pattern of disordered activation in AD is more compatible with an over-sensitive reward system, a deficit in control systems or a combination of both to produce the high risk-taking behavior observed in alcohol dependents (ADs). Here, alcohol cues were used in an ecological decisions-to-drink task that involved high- and low-risk scenarios where the chance of serious negative imagined consequences was varied. Non-alcohol cues were included as control stimuli. Functional magnetic resonance imaging (fMRI) was used to measure blood oxygen level-dependent (BOLD) signal change in 15 alcohol-dependent and 16 control women. This design allowed us to address two major questions concerning AD: first, is there a specific pattern of disordered activation that drives the heightened endorsement of high-risk decisions-to-drink in ADs? And, second, is that pattern specific to decisions-to-drink or does it generalize to other appetitive and/or neutral cues? The results showed that, during high-risk decisions-to-drink, alcohol-dependent women activated reward circuits, cognitive control circuits and regions of the default-mode network (DMN), while control women deactivated approach circuits and showed enhanced activation in regions of the DMN. Group differences were found only for decisions-to-drink, suggesting that they are specific to alcohol cues. Simultaneous activation of reward networks, cognitive control networks and the DMN in alcohol-dependent women suggests that over-endorsement of high-risk drinking decisions by alcohol-dependent women may be due to a problem with switching between different neural networks.
--- ABSTRACT END ---
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[frequency of next (right) word to due to]
(1)115 the (10)4 insufficient (19)2 cardiac (28)2 pannus
(2)30 its (11)3 changes (20)2 common (29)2 potential
(3)30 their (12)3 increased (21)2 condom (30)2 previous
(4)20 a (13)3 low (22)2 environmental (31)2 primary
(5)9 an (14)3 multiple (23)2 extreme (32)2 progressive
(6)5 limited (15)3 poor (24)2 inadequate (33)2 prolonged
(7)4 differences (16)3 possible (25)2 inflammation (34)2 similarities
(8)4 different (17)2 abnormal (26)2 lack (35)2 some
(9)4 high (18)2 anthropogenic (27)2 major

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--- WordNet output for due --- =>1.予定の, 支払期日がきて, 当然支払われるべき, 2.支払[提出]期日, 満期日, 会費 Overview of noun due The noun due has 2 senses (first 1 from tagged texts) 1. (4) due -- (that which is deserved or owed; "give the devil his due") 2. due -- (a payment that is due (e.g., as the price of membership); "the society dropped him for non-payment of dues") Overview of adj due The adj due has 4 senses (first 2 from tagged texts) 1. (6) due -- (owed and payable immediately or on demand; "payment is due") 2. (1) due -- (scheduled to arrive; "the train is due in 15 minutes") 3. due -- (suitable to or expected in the circumstances; "all due respect"; "due cause to honor them"; "a long due promotion"; "in due course"; "due esteem"; "exercising due care") 4. ascribable, due, imputable, referable -- (capable of being assigned or credited to; "punctuation errors ascribable to careless proofreading"; "the cancellation of the concert was due to the rain"; "the oversight was not imputable to him") Overview of adv due The adv due has 1 sense (no senses from tagged texts) 1. due -- (directly or exactly; straight; "went due North") --- WordNet end ---