ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
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kwic search for found out of >500 occurrences
581812 occurrences (No.15 in the rank) during 5 years in the PubMed. [cache]
145) It was found that PEMF promoted the viability rate of both cell types, whereas DHEA decreased the viability rate in a concentration-dependent manner.
2015 Journal of tissue engineering and regenerative medicine
* The effect of pulsed electromagnetic fields and dehydroepiandrosterone on viability and osteo-induction of human mesenchymal stem cells.
- The hypothesis of this work was that human bone marrow-derived mesenchymal stem cells (MSCs) are regulated by pulsed electromagnetic fields (PEMFs) and by intracrine conversion of an adrenal prohormone to dihydrotestosterone. The effect of PEMF and dehydroepiandrosterone (DHEA) on viability and osteogenic differentiation of human MSCs and on the viability of osteoblastic SaOS-2 cells was evaluated. It was found that PEMF promoted the viability rate of both cell types, whereas DHEA decreased the viability rate in a concentration-dependent manner. PEMF did not have major effects on osteo-induction at this low seeding density level (3000 cells/cm(2) ). Instead, DHEA, after MSC-mediated and 5α-reductase-dependent conversion to dihydrotestosterone, clearly promoted the osteo-induction of MSCs induced with β-glyserophosphate, ascorbate and dexamethasone. Alkaline phosphatase (ALP), SMAD1, RUNX2, osteopontin (OP) and osteocalcin (OC) RNA levels were increased and alizarin red S- and hydroxyapatite-specific OsteoImage(TM) stainings disclosed a promoted mineralization process. In addition, DHEA increased OP and OC mRNA levels of non-induced MSCs. A sequential use of mitogenic PEMF early during the fracture healing, followed by later administration of DHEA with osteogenic differentiating effect, might be worth subjecting to a randomized clinical trial.
=>設立する, 基礎づける
Overview of noun found
The noun found has 1 sense (first 1 from tagged texts)
1. (1) found -- (food and lodging provided in addition to money; "they worked for $30 and found")
Overview of verb found
The verb found has 3 senses (first 2 from tagged texts)
1. (9) establish, set up, found, launch -- (set up or found; "She set up a literacy program")
2. (4) establish, found, plant, constitute, institute -- (set up or lay the groundwork for;
"establish a new department")
3. establish, base, ground, found -- (use as a basis for; found on; "base a claim on some
observation")
Overview of verb find
The verb find has 16 senses (first 13 from tagged texts)
1. (159) find, happen, chance, bump, encounter -- (come upon, as if by accident; meet with; "We find
this idea in Plato"; "I happened upon the most wonderful bakery not very far from here"; "She
chanced upon an interesting book in the bookstore the other day")
2. (141) detect, observe, find, discover, notice -- (discover or determine the existence, presence,
or fact of; "She detected high levels of lead in her drinking water"; "We found traces of lead in
the paint")
3. (86) find, regain -- (come upon after searching; find the location of something that was missed
or lost; "Did you find your glasses?"; "I cannot find my gloves!")
4. (57) determine, find, find out, ascertain -- (establish after a calculation, investigation,
experiment, survey, or study; "find the product of two numbers"; "The physicist who found the
elusive particle won the Nobel Prize")
5. (57) find, feel -- (come to believe on the basis of emotion, intuitions, or indefinite grounds;
"I feel that he doesn't like me"; "I find him to be obnoxious"; "I found the movie rather
entertaining")
6. (45) witness, find, see -- (perceive or be contemporaneous with; "We found Republicans winning
the offices"; "You'll see a lot of cheating in this school"; "The 1960's saw the rebellion of the
younger generation against established traditions"; "I want to see results")
7. (41) line up, get hold, come up, find -- (get something or somebody for a specific purpose; "I
found this gadget that will serve as a bottle opener"; "I got hold of these tools to fix our
plumbing"; "The chairman got hold of a secretary on Friday night to type the urgent letter")
8. (34) discover, find -- (make a discovery, make a new finding; "Roentgen discovered X-rays";
"Physicists believe they found a new elementary particle")
9. (29) discover, find -- (make a discovery; "She found that he had lied to her"; "The story is
false, so far as I can discover")
10. (16) find -- (obtain through effort or management; "She found the time and energy to take care
of her aging parents"; "We found the money to send our sons to college")
11. (16) rule, find -- (decide on and make a declaration about; "find someone guilty")
12. (13) receive, get, find, obtain, incur -- (receive a specified treatment (abstract); "These
aspects of civilization do not find expression or receive an interpretation"; "His movie received a
good review"; "I got nothing but trouble for my good intentions")
13. (11) find -- (perceive oneself to be in a certain condition or place; "I found myself in a
difficult situation"; "When he woke up, he found himself in a hospital room")
14. recover, retrieve, find, regain -- (get or find back; recover the use of; "She regained control
of herself"; "She found her voice and replied quickly")
15. find -- (succeed in reaching; arrive at; "The arrow found its mark")
16. find oneself, find -- (accept and make use of one's personality, abilities, and situation; "My
son went to Berkeley to find himself")
Overview of adj found
The adj found has 1 sense (first 1 from tagged texts)
1. (1) found -- (come upon unexpectedly or after searching; "found art"; "the lost-and-found
department")
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