ELIZA

return kwic search for functional out of >500 occurrences
267449 occurrences (No.100 in the rank) during 5 years in the PubMed. [cache]

29) We conducted trial-by-trial analyses on data from 137 healthy participants who underwent a two-day fear conditioning and extinction paradigm in a functional magnetic resonance imaging (fMRI) scanner.

--- ABSTRACT ---

PMID:34126211 DOI:10.1016/j.neuroimage.2021.118261

2021 NeuroImage

* Fear extinction learning modulates large-scale brain connectivity.

- Exploring the neural circuits of the extinction of conditioned fear is critical to advance our understanding of fear- and anxiety-related disorders. The field has focused on examining the role of various regions of the medial prefrontal cortex, insular cortex, hippocampus, and amygdala in conditioned fear and its extinction. The contribution of this 'fear network' to the conscious awareness of fear has recently been questioned. And as such, there is a need to examine higher/multiple cortical systems that might contribute to the conscious feeling of fear and anxiety. Herein, we studied functional connectivity patterns across the entire brain to examine the contribution of multiple networks to the acquisition of fear extinction learning and its retrieval. We conducted trial-by-trial analyses on data from 137 healthy participants who underwent a two-day fear conditioning and extinction paradigm in a functional magnetic resonance imaging (fMRI) scanner. We found that functional connectivity across a broad range of brain regions, many of which are part of the default mode, frontoparietal, and ventral attention networks, increased from early to late extinction learning only to a conditioned cue. The increased connectivity during extinction learning predicted the magnitude of extinction memory tested 24 h later. Together, these findings provide evidence supporting recent studies implicating distributed brain regions in learning, consolidation and expression of fear extinction memory in the human brain.

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[frequency of next (right) word to functional]

(1)24 connectivity	(20)4 brain	(39)3 material	(58)2 interactions
(2)14 magnetic	(21)4 changes	(40)3 materials	(59)2 interpretation
(3)13 and	(22)4 group	(41)3 organization	(60)2 neuroimaging
(4)13 recovery	(23)4 implications	(42)3 tasks	(61)2 organ
(5)11 role	(24)4 networks	(43)3 units	(62)2 outcome
(6)8 analyses	(25)4 training+CPM	(44)2 Threshold	(63)2 outcome,
(7)8 assays	(26)3 null	(45)2 academics,	(64)2 outcomes,
(8)8 groups	(27)3 activation	(46)2 alteration	(65)2 phenotypes
(9)8 outcomes	(28)3 activity	(47)2 antibodies	(66)2 plasticity
(10)8 roles	(29)3 annotation	(48)2 architecture	(67)2 profile
(11)8 training	(30)3 attributes	(49)2 characterization	(68)2 rating
(12)6 MRI	(31)3 capacity	(50)2 consequence	(69)2 reconstruction
(13)6 analysis	(32)3 cure	(51)2 defects	(70)2 redundancy
(14)6 properties	(33)3 effector	(52)2 differences	(71)2 relationship
(15)6 studies	(34)3 effects	(53)2 diversification	(72)2 relevance
(16)5 consequences	(35)3 enrichment	(54)2 enzymes	(73)2 selectivity
(17)5 impairment	(36)3 foods	(55)2 evaluation
(18)5 network	(37)3 impact	(56)2 groups,
(19)5 theory	(38)3 limitations	(57)2 integrity

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--- WordNet output for functional --- =>機能の, 関数の, 機能する, 機能上の, 実用的な, 機能的な Overview of adj functional The adj functional has 6 senses (first 2 from tagged texts) 1. (3) functional -- (designed for or capable of a particular function or use; "a style of writing in which every word is functional"; "functional architecture") 2. (1) functional -- (involving or affecting function rather than physiology; "functional deafness") 3. functional -- (relating to or based on function especially as opposed to structure; "the problem now is not a constitutional one; it is a functional one"; "delegates elected on a functional rather than a geographical basis") 4. functional, usable, useable, operable, operational -- (fit or ready for use or service; "the toaster was still functional even after being dropped"; "the lawnmower is a bit rusty but still usable"; "an operational aircraft"; "the dishwasher is now in working order") 5. functional -- (designed for or adapted to a function or use; "functional education selects knowledge that is concrete and usable rather than abstract and theoretical"; "functional architecture") 6. running, operative, functional, working -- ((of e.g. a machine) performing or capable of performing; "in running (or working) order"; "a functional set of brakes") --- WordNet end ---