ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for functional out of >500 occurrences
267449 occurrences (No.100 in the rank) during 5 years in the PubMed. [no cache] 500 found
4) Functional magnetic resonance imaging (fMRI) was used to measure blood oxygen level-dependent (BOLD) signal change in 15 alcohol-dependent and 16 control women.
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PMID:24373127 DOI:10.1111/adb.12121
2015 Addiction biology
* Neural mechanisms of high-risk decisions-to-drink in alcohol-dependent women.
- A hallmark of alcohol dependence (AD) is continually drinking despite the risk of negative consequences. Currently, it is not known if the pattern of disordered activation in AD is more compatible with an over-sensitive reward system, a deficit in control systems or a combination of both to produce the high risk-taking behavior observed in alcohol dependents (ADs). Here, alcohol cues were used in an ecological decisions-to-drink task that involved high- and low-risk scenarios where the chance of serious negative imagined consequences was varied. Non-alcohol cues were included as control stimuli. Functional magnetic resonance imaging (fMRI) was used to measure blood oxygen level-dependent (BOLD) signal change in 15 alcohol-dependent and 16 control women. This design allowed us to address two major questions concerning AD: first, is there a specific pattern of disordered activation that drives the heightened endorsement of high-risk decisions-to-drink in ADs? And, second, is that pattern specific to decisions-to-drink or does it generalize to other appetitive and/or neutral cues? The results showed that, during high-risk decisions-to-drink, alcohol-dependent women activated reward circuits, cognitive control circuits and regions of the default-mode network (DMN), while control women deactivated approach circuits and showed enhanced activation in regions of the DMN. Group differences were found only for decisions-to-drink, suggesting that they are specific to alcohol cues. Simultaneous activation of reward networks, cognitive control networks and the DMN in alcohol-dependent women suggests that over-endorsement of high-risk drinking decisions by alcohol-dependent women may be due to a problem with switching between different neural networks.
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(1)50 magnetic (18)4 gastrointestinal (35)3 integration (52)2 connections
(2)38 connectivity (19)4 outcome (36)3 interactions (53)2 differentiation
(3)29 and (20)4 outcomes (37)3 movement (54)2 domains
(4)8 limitations (21)4 relationships (38)3 single (55)2 endurance
(5)7 network (22)4 unit (39)3 status (56)2 health
(6)7 recovery (23)3 Assessment (40)3 status, (57)2 imaging
(7)7 role (24)3 MRI (41)3 studies (58)2 impact
(8)6 changes (25)3 Well-Being (42)2 CD133 (59)2 integrity
(9)6 results (26)3 activation (43)2 HL (60)2 losses
(10)5 alterations (27)3 brain (44)2 ability (61)2 networks
(11)5 limitation (28)3 consequences (45)2 activity (62)2 neuronal
(12)5 neuroimaging (29)3 coupling (46)2 analyses (63)2 organization
(13)5 properties (30)3 decline (47)2 as (64)2 parameters
(14)5 theory (31)3 deficits (48)2 assays (65)2 roles
(15)4 capacity (32)3 differences (49)2 assessment (66)2 significance
(16)4 connectivity, (33)3 impairment (50)2 characteristics (67)2 specialization
(17)4 foods (34)3 improvement (51)2 cognitive

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--- WordNet output for functional --- =>機能の, 関数の, 機能する, 機能上の, 実用的な, 機能的な Overview of adj functional The adj functional has 6 senses (first 2 from tagged texts) 1. (3) functional -- (designed for or capable of a particular function or use; "a style of writing in which every word is functional"; "functional architecture") 2. (1) functional -- (involving or affecting function rather than physiology; "functional deafness") 3. functional -- (relating to or based on function especially as opposed to structure; "the problem now is not a constitutional one; it is a functional one"; "delegates elected on a functional rather than a geographical basis") 4. functional, usable, useable, operable, operational -- (fit or ready for use or service; "the toaster was still functional even after being dropped"; "the lawnmower is a bit rusty but still usable"; "an operational aircraft"; "the dishwasher is now in working order") 5. functional -- (designed for or adapted to a function or use; "functional education selects knowledge that is concrete and usable rather than abstract and theoretical"; "functional architecture") 6. running, operative, functional, working -- ((of e.g. a machine) performing or capable of performing; "in running (or working) order"; "a functional set of brakes") --- WordNet end ---