ELIZA

return kwic search for further out of >500 occurrences
298283 occurrences (No.79 in the rank) during 5 years in the PubMed. [no cache] 500 found

94) Further study to emphasise the role of topical sildenafil in the prevention or treatment of PrUs in hospitalised patients is required.

--- ABSTRACT ---

PMID:23731453 DOI:10.1111/iwj.12104

2015 International wound journal

* Sildenafil in the treatment of pressure ulcer: a randomised clinical trial.

- Pressure ulcer (PrU)-related hospitalisation and mortality are critical issues in medical and surgical patients. Although animal studies have suggested the beneficial effects of sildenafil on wound healing, related clinical data are lacking. This is the first clinical study that has evaluated the effects of topical sildenafil on PrU healing in human subjects. Enrolled patients were randomly allocated to receive topical sildenafil (10%) ointment or placebo daily. Wound healing was assessed visually and photographically by the change in wound score according to two-digit Stirling scale. Decreases in grades of the PrUs were significantly higher in sildenafil group compared with placebo group (P < 0·001). In addition, surface areas of ulcers in sildenafil group were significantly reduced compared to the control group at day 14 of intervention (P = 0·007). It appears that these effects may be mediated by improvement of microvascular reperfusion in the skin and soft tissue. Further study to emphasise the role of topical sildenafil in the prevention or treatment of PrUs in hospitalised patients is required.

--- ABSTRACT END ---

[
right
kwic]

[frequency of next (right) word to further]

(1)39 studies	(16)4 developed	(31)2 analyses	(46)2 insights
(2)32 research	(17)4 in	(32)2 analyzed	(47)2 monitoring
(3)18 investigation	(18)4 supported	(33)2 application	(48)2 optimization
(4)18 study	(19)3 null	(34)2 as	(49)2 prospective
(5)11 the	(20)3 a	(35)2 assessed	(50)2 protection
(6)10 investigations	(21)3 clinical	(36)2 complications	(51)2 spread
(7)8 analysis	(22)3 evaluation	(37)2 divided	(52)2 suggests
(8)7 evidence	(23)3 exploration	(38)2 elucidate	(53)2 supporting
(9)7 phylogenetic	(24)3 explore	(39)2 enhance	(54)2 supports
(10)6 explored	(25)3 for	(40)2 episodes	(55)2 taxonomic
(11)5 development	(26)3 increased	(41)2 evaluated	(56)2 that
(12)5 support	(27)3 investigate	(42)2 examination	(57)2 used
(13)5 validation	(28)3 molecular	(43)2 identification
(14)4 by	(29)3 understand	(44)2 improvement
(15)4 confirmed	(30)2 advances	(45)2 increase

add keyword

--- WordNet output for further --- =>1.さらにずっと, さらに先に, 一層遠く, その上, 更に, もっと遠い, なお一層の, さらに遠く, もっと先に, いっそうはるかに, さらにまた, さらになお(furthermore), 2.進める, 助成する, 促進する Overview of verb further The verb further has 2 senses (first 2 from tagged texts) 1. (7) foster, further -- (promote the growth of; "Foster our children's well-being and education") 2. (2) promote, advance, boost, further, encourage -- (contribute to the progress or growth of; "I am promoting the use of computers in the classroom") Overview of adj further The adj further has 1 sense (first 1 from tagged texts) 1. (2) further, farther -- (more distant in especially degree; "nothing could be further from the truth"; "further from our expectations"; "farther from the truth"; "farther from our expectations") Overview of adv further The adv further has 3 senses (first 3 from tagged texts) 1. (33) further, farther -- (to or at a greater extent or degree or a more advanced stage (`further' is used more often than `farther' in this abstract sense); "further complicated by uncertainty about the future"; "let's not discuss it further"; "nothing could be further from the truth"; "they are further along in their research than we expected"; "the application of the law was extended farther"; "he is going no farther in his studies") 2. (10) further -- (in addition or furthermore; "if we further suppose"; "stated further that he would not cooperate with them"; "they are definitely coming; further, they should be here already") 3. (1) farther, further -- (to or at a greater distance in time or space (`farther' is used more frequently than `further' in this physical sense); "farther north"; "moved farther away"; "farther down the corridor"; "the practice may go back still farther to the Druids"; "went only three miles further"; "further in the future") Overview of adv far The adv far has 5 senses (first 4 from tagged texts) 1. (61) far -- (to a considerable degree; very much; "a far far better thing that I do"; "felt far worse than yesterday"; "eyes far too close together") 2. (39) far -- (at or to or from a great distance in space; "he traveled far"; "strayed far from home"; "sat far away from each other") 3. (22) far -- (at or to a certain point or degree; "I can only go so far before I have to give up"; "how far can we get with this kind of argument?") 4. (3) far -- (remote in time; "if we could see far into the future"; "all that happened far in the past") 5. far -- (to an advanced stage or point; "a young man who will go very far") --- WordNet end ---