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403337 occurrences (No.43 in the rank) during 5 years in the PubMed. [cache]
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403337 occurrences (No.43 in the rank) during 5 years in the PubMed. [cache]
| 26) The objective of the present study was to investigate STAT5A gene expression during early bovine embryogenesis. |
| PMID:23981721 DOI:10.1017/S0967199413000427 |
| 2015 Zygote (Cambridge, England) |
| * Expression pattern of STAT5A gene during early bovine embryogenesis. |
| - Growth hormone (GH) plays an important role in early embryo development. It has been shown to activate multiple pathways, the most comprehensively studied being the STAT/JAK (Signal transducers and activators of transcription/Janus kinase) pathway. The objective of the present study was to investigate STAT5A gene expression during early bovine embryogenesis. Real-time polymerase chain reaction (RT-PCR) was used to measure the abundance of STAT5A transcripts. The mRNA was present at all stages of preimplantation bovine embryos investigated. The most abundant STAT5A expression occurred at the 2-cell stage. Expression was markedly reduced between the 4-cell and 8-cell stages, coinciding with the known time of embryo genome activation and loss of maternal mRNAs. This finding suggests that the embryonic STAT5A gene is primarily activated by maternal gene products. |
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(18)4 activation |
(32)3 polymorphisms |
(46)2 peptide |
| (5)21 *null* | (19)4 delivery |
(33)3 sequencing |
(47)2 profiling |
| (6)15 was |
(20)4 encoding |
(34)3 transcription |
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| (7)12 expression, |
(21)4 expressions |
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| (10)7 organization |
(24)4 silencing |
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| (11)7 sequences |
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(39)2 content |
(53)2 therapy, |
| (12)5 flow |
(26)4 which |
(40)2 family |
(54)2 used |
| (13)5 for |
(27)3 alterations |
(41)2 from |
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| (14)5 in |
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--- WordNet output for gene ---