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- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for growth out of >500 occurrences
309169 occurrences (No.70 in the rank) during 5 years in the PubMed. [no cache] 500 found
15) Embryos were exposed in vitro to various concentrations of DCF, that is, 0, 3.75, 7.5 and 15 µg/ml for 24 h, respectively, and examined for the growth and differentiation at the end of the culture period for the presence of any specific malformations.
--- ABSTRACT ---
PMID:23456812 DOI:10.1177/0748233713480209
2015 Toxicology and industrial health
* Role of apoptosis in mediating diclofenac-induced teratogenesis: An in vitro approach.
- Diclofenac (DCF) is among the most commonly used nonsteroidal anti-inflammatory drugs worldwide for the treatment of various conditions in postpubertal women. However, very limited information is available regarding its safety during pregnancy and teratogenecity. The present study was designed to elucidate the effects of DCF on the developing rat embryos during the major organogenesis period and investigate the critical role of apoptosis in bringing about these congenital anomalies. Embryos were exposed in vitro to various concentrations of DCF, that is, 0, 3.75, 7.5 and 15 µg/ml for 24 h, respectively, and examined for the growth and differentiation at the end of the culture period for the presence of any specific malformations. Growth and developmental parameters such as weight of embryos, crown-rump length and number of somites were found to be lower in the embryos exposed to high concentrations of DCF (7.5 and 15.0 μg/ml) when compared with the untreated control. However, no significant difference in growth parameters was found between embryos exposed to 3.75 µg/ml and the control group. In parallel to this, flow cytometric analysis and DNA quantitation of cultured rat embryos were performed to verify the involvement of apoptosis in mediating DCF-induced teratogenesis. A concentration-dependent increase in apoptosis in embryos suggests a possible engagement of apoptosis in the role of DCF as a teratogenic agent. A detailed analysis of the actual effect of DCF on cellular apoptotic machinery necessitates further evaluation.
--- ABSTRACT END ---
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[frequency of next (right) word to growth]
(1)69 and (12)5 at (25)3 models (36)2 model
(2)48 factor (13)4 but (26)3 or (37)2 modeling
(3)48 of (14)4 during (27)3 traits (38)2 outcomes
(4)41 *null* (15)4 factor, (28)3 trajectories (39)2 phase
(5)32 in (17)4 patterns (29)2 among (40)2 properties
(6)25 factors (18)4 plate (30)2 are (41)2 responses
(7)9 inhibition (19)4 response (31)2 as (42)2 restriction
(8)8 rate (20)4 was (32)2 dynamics (43)2 stunting
(9)6 factors, (21)3 cone (33)2 effects (44)2 to
(10)6 rates (22)3 curve (34)2 forest (45)2 velocities
(11)5 arrest (23)3 factor-C (35)2 hormone (46)2 were

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--- WordNet output for growth --- =>茂み, 成長, 増加, 発展, 栽培, 腫よう, 成長物 Overview of noun growth The noun growth has 7 senses (first 5 from tagged texts) 1. (37) growth, growing, maturation, development, ontogeny, ontogenesis -- ((biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level; "he proposed an indicator of osseous development in children") 2. (20) growth -- (a progression from simpler to more complex forms; "the growth of culture") 3. (3) increase, increment, growth -- (a process of becoming larger or longer or more numerous or more important; "the increase in unemployment"; "the growth of population") 4. (3) growth -- (vegetation that has grown; "a growth of trees"; "the only growth was some salt grass") 5. (1) emergence, outgrowth, growth -- (the gradual beginning or coming forth; "figurines presage the emergence of sculpture in Greece") 6. growth -- ((pathology) an abnormal proliferation of tissue (as in a tumor)) 7. growth -- (something grown or growing; "a growth of hair") --- WordNet end ---