ELIZA

return kwic search for health out of >500 occurrences
353463 occurrences (No.52 in the rank) during 5 years in the PubMed. [cache]

215) Recently, the large epidemic of HFMD caused by HEV infection became a growing threat to public health in China.

--- ABSTRACT ---

PMID:23919297 DOI:10.3109/1040841X.2013.813903

2015 Critical reviews in microbiology

* The interaction between human enteroviruses and type I IFN signaling pathway.

- Human enteroviruses (HEV), very common and important human pathogens, cause infections in diverse ways. Recently, the large epidemic of HFMD caused by HEV infection became a growing threat to public health in China. As the first line of immune response, the type I interferon (IFN-α/β) pathway plays an essential role in antiviral infection, particularly in limiting both the early and late stages of infection. Because of co-evolution with the host, the viruses have evolved multiple strategies to evade or subvert the host immunity to ensure their survival. In this paper, we systematically reviewed and summarized the interaction between HEV infections and host type I IFN responses. We firstly described the recent findings of HEV recognition and IFN induction, specifically on host pattern-recognition receptors (PRRs) in HEV infection. Then we discussed the antiviral effect of IFN in HEV infection. Finally, we timely summarized the mechanisms of HEV to circumvent the IFN responses. Clarification of the complexity in this battle may provide us new strategies for prevention and antiviral treatment.

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[frequency of next (right) word to health]

(1)73 care	(17)5 impact	(33)3 issues	(49)2 cost
(2)35 and	(18)5 impacts	(34)3 literacy	(50)2 data
(3)23 null	(19)5 insurance	(35)3 policy	(51)2 economic
(4)13 promotion	(20)5 problem	(36)3 risk	(52)2 examination
(5)12 Survey	(21)5 system	(37)3 risks	(53)2 factors
(6)12 professionals	(22)4 knowledge	(38)3 services,	(54)2 hazard
(7)8 education	(23)4 providers	(39)3 symptoms	(55)2 is
(8)8 effects	(24)4 surveillance	(40)3 was	(56)2 messages
(9)8 outcomes	(25)3 Insurance	(41)3 workers	(57)2 needs
(10)8 status	(26)3 Promotion	(42)2 Department	(58)2 plan
(11)7 problems	(27)3 as	(43)2 Organization's	(59)2 protection
(12)6 Organization	(28)3 authorities	(44)2 activities	(60)2 sector
(13)6 in	(29)3 centres	(45)2 benefits	(61)2 survey
(14)6 of	(30)3 conditions	(46)2 centers
(15)6 services	(31)3 hazards	(47)2 challenges
(16)5 behaviours	(32)3 interventions	(48)2 concern

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--- WordNet output for health --- =>健康状態, 健康, 調子 Overview of noun health The noun health has 2 senses (first 1 from tagged texts) 1. (21) health, wellness -- (a healthy state of wellbeing free from disease; "physicians should be held responsible for the health of their patients") 2. health -- (the general condition of body and mind; "his delicate health"; "in poor health") --- WordNet end ---