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return kwic search for high out of >500 occurrences
636281 occurrences (No.11 in the rank) during 5 years in the PubMed. [no cache] 500 found

157) In conclusion, a representative DTI deterioration model was established by concentrating high shear stress in deep tissues while minimising shear stress in the overlying skin.

--- ABSTRACT ---

PMID:23651215 DOI:10.1111/iwj.12082

2015 International wound journal

* Establishment of a novel rat model for deep tissue injury deterioration.

- Deep tissue injuries (DTIs) can become significant problems because of their rapid deterioration into deep pressure ulcers. Presently, no animal model of DTI deterioration has been developed. By concentrating pressure and shear stress in deep tissues while minimising pressure and shear stress in the overlying skin, we produced an effective rat model of DTI deterioration. Two-dimensional finite element method (FEM) simulated the distribution of pressure and shear stress under several pressure-loading conditions. FEM showed that concentrated shear stress in deep tissue with minimum shear stress in the overlying skin could be created by using a prominence and a cushion, respectively. On the basis of the results of FEM analysis, we selected suitable conditions for testing the rat DTI deterioration model. The compressed area was macroscopically observed until day 13, and histopathologic analysis via haematoxylin and eosin (H&E) staining was performed on days 3, 7 and 13. H&E staining showed that the distribution of tissue damage was similar to the predicted FEM results. Deep ulceration and tissue damage extending from deep tissues to the overlying skin and surrounding tissues were observed in the DTI deterioration model, which are similar to the clinical manifestations of DTI deterioration. In conclusion, a representative DTI deterioration model was established by concentrating high shear stress in deep tissues while minimising shear stress in the overlying skin. This model will allow a better understanding of the mechanisms behind DTI deterioration and the development of preventative strategies.

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(1)18 risk	(19)4 gamma	(37)2 AT	(55)2 importance
(2)14 and	(20)4 group	(38)2 N/L	(56)2 index
(3)12 prevalence	(21)4 patient	(39)2 PbB	(57)2 inter-specific
(4)10 levels	(22)4 rate	(40)2 accuracy	(58)2 internal
(5)9 level	(23)4 shear	(41)2 age	(59)2 job
(6)9 school	(24)3 blood	(42)2 alcohol	(60)2 mass
(7)8 null	(25)3 concentration	(43)2 areas	(61)2 population
(8)7 proportion	(26)3 density	(44)2 birth	(62)2 positive
(9)6 in	(27)3 dose	(45)2 caries	(63)2 production
(10)6 lipoprotein	(28)3 efficiency	(46)2 chemotherapy	(64)2 profile
(11)6 liquid	(29)3 frequency	(47)2 correlation	(65)2 relative
(12)6 mortality	(30)3 genetic	(48)2 dental	(66)2 reliability
(13)5 as	(31)3 groups	(49)2 diet	(67)2 resistance
(14)5 autism	(32)3 incidence	(50)2 exposure	(68)2 risks'
(15)5 degree	(33)3 patients	(51)2 expression	(69)2 specificity,
(16)4 concentrations	(34)3 rates	(52)2 frequencies	(70)2 technologies
(17)4 doses	(35)3 ulnar	(53)2 heart	(71)2 tumours
(18)4 for	(36)2 ASD	(54)2 hydrostatic	(72)2 variability

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--- WordNet output for high --- =>1.高いところにある, 高い, 高さが〜の, 高貴な, 高く, 高額の, 興奮状態の, 2.高い所, 高水準 Overview of noun high The noun high has 7 senses (first 1 from tagged texts) 1. (5) high -- (a lofty level or position or degree; "summer temperatures reached an all-time high") 2. high -- (an air mass of higher than normal pressure; "the east coast benefits from a Bermuda high") 3. high -- (a state of sustained elation; "I'm on a permanent high these days") 4. high -- (a state of altered consciousness induced by alcohol or narcotics; "they took drugs to get a high on") 5. high, heights -- (a high place; "they stood on high and observed the countryside"; "he doesn't like heights") 6. senior high school, senior high, high, highschool, high school -- (a public secondary school usually including grades 9 through 12; "he goes to the neighborhood highschool") 7. high gear, high -- (a forward gear with a gear ratio that gives the greatest vehicle velocity for a given engine speed) Overview of adj high The adj high has 7 senses (first 5 from tagged texts) 1. (134) high -- (greater than normal in degree or intensity or amount; "a high temperature"; "a high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high"; "he has a high opinion of himself") 2. (51) high -- ((literal meaning) being at or having a relatively great or specific elevation or upward extension (sometimes used in combinations like `knee-high'); "a high mountain"; "high ceilings"; "high buildings"; "a high forehead"; "a high incline"; "a foot high") 3. (10) eminent, high -- (standing above others in quality or position; "people in high places"; "the high priest"; "eminent members of the community") 4. (7) high, high-pitched -- (used of sounds and voices; high in pitch or frequency) 5. (2) high, in high spirits -- (happy and excited and energetic) 6. gamey, gamy, high -- ((used of the smell of meat) smelling spoiled or tainted) 7. high, mellow -- (slightly and pleasantly intoxicated from alcohol or a drug (especially marijuana)) Overview of adv high The adv high has 4 senses (first 2 from tagged texts) 1. (9) high, high up -- (at a great altitude; "he climbed high on the ladder") 2. (2) high -- (in or to a high position, amount, or degree; "prices have gone up far too high") 3. high, richly, luxuriously -- (in a rich manner; "he lives high") 4. high -- (far up toward the source; "he lives high up the river") --- WordNet end ---