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return kwic search for high out of >500 occurrences
636281 occurrences (No.11 in the rank) during 5 years in the PubMed. [no cache] 500 found

164) The high concentration of trophic factors contained in the granules of platelets, have led to suggest that the application of platelet-rich plasma can help to stimulate or accelerate the repair or regeneration of a number of tissues.

--- ABSTRACT ---

PMID:23461926 DOI:10.1177/1753193413481937

2015 Cirugia y cirujanos

* [Platelets-rich plasma: a versatile tool for regenerative medicine?].

- Platelet-rich plasma is a blood product concentrate obtained by centrifugation of whole blood that is characterized by a high concentration of platelets (4 to 6 times their normal values). The high concentration of trophic factors contained in the granules of platelets, have led to suggest that the application of platelet-rich plasma can help to stimulate or accelerate the repair or regeneration of a number of tissues. Since their first application in the treatment of skin ulcers in 1980, a considerable number of novel applications in different fields of medicine have emerged (Ophthalmology, Otorhinolaryngology, Maxillofacial Surgery surgical wounds, musculoskeletal disorders, burns, Esthetic Surgery, repair of peripheral nerves, etc.), some of these applications with clearly positive or very promising results. Despite the large amount of experimental and clinical literature about the usefulness of platelet-rich plasma in different areas of regenerative medicine, there are few therapeutic indications in which it is fully demonstrated its effectiveness. This fact highlights the importance of carry out methodologically appropriate clinical trials in the near future, in order to improve the evidence level of platelet-rich plasma treatment. The purpose of this article is to perform an update and critical review about the biological basis of platelet-rich plasma, to review indications for which there is more scientific support on its use, and finally to describe their new indications that are currently under research.

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(1)18 risk	(19)4 gamma	(37)2 AT	(55)2 importance
(2)14 and	(20)4 group	(38)2 N/L	(56)2 index
(3)12 prevalence	(21)4 patient	(39)2 PbB	(57)2 inter-specific
(4)10 levels	(22)4 rate	(40)2 accuracy	(58)2 internal
(5)9 level	(23)4 shear	(41)2 age	(59)2 job
(6)9 school	(24)3 blood	(42)2 alcohol	(60)2 mass
(7)8 null	(25)3 concentration	(43)2 areas	(61)2 population
(8)7 proportion	(26)3 density	(44)2 birth	(62)2 positive
(9)6 in	(27)3 dose	(45)2 caries	(63)2 production
(10)6 lipoprotein	(28)3 efficiency	(46)2 chemotherapy	(64)2 profile
(11)6 liquid	(29)3 frequency	(47)2 correlation	(65)2 relative
(12)6 mortality	(30)3 genetic	(48)2 dental	(66)2 reliability
(13)5 as	(31)3 groups	(49)2 diet	(67)2 resistance
(14)5 autism	(32)3 incidence	(50)2 exposure	(68)2 risks'
(15)5 degree	(33)3 patients	(51)2 expression	(69)2 specificity,
(16)4 concentrations	(34)3 rates	(52)2 frequencies	(70)2 technologies
(17)4 doses	(35)3 ulnar	(53)2 heart	(71)2 tumours
(18)4 for	(36)2 ASD	(54)2 hydrostatic	(72)2 variability

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--- WordNet output for high --- =>1.高いところにある, 高い, 高さが〜の, 高貴な, 高く, 高額の, 興奮状態の, 2.高い所, 高水準 Overview of noun high The noun high has 7 senses (first 1 from tagged texts) 1. (5) high -- (a lofty level or position or degree; "summer temperatures reached an all-time high") 2. high -- (an air mass of higher than normal pressure; "the east coast benefits from a Bermuda high") 3. high -- (a state of sustained elation; "I'm on a permanent high these days") 4. high -- (a state of altered consciousness induced by alcohol or narcotics; "they took drugs to get a high on") 5. high, heights -- (a high place; "they stood on high and observed the countryside"; "he doesn't like heights") 6. senior high school, senior high, high, highschool, high school -- (a public secondary school usually including grades 9 through 12; "he goes to the neighborhood highschool") 7. high gear, high -- (a forward gear with a gear ratio that gives the greatest vehicle velocity for a given engine speed) Overview of adj high The adj high has 7 senses (first 5 from tagged texts) 1. (134) high -- (greater than normal in degree or intensity or amount; "a high temperature"; "a high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high"; "he has a high opinion of himself") 2. (51) high -- ((literal meaning) being at or having a relatively great or specific elevation or upward extension (sometimes used in combinations like `knee-high'); "a high mountain"; "high ceilings"; "high buildings"; "a high forehead"; "a high incline"; "a foot high") 3. (10) eminent, high -- (standing above others in quality or position; "people in high places"; "the high priest"; "eminent members of the community") 4. (7) high, high-pitched -- (used of sounds and voices; high in pitch or frequency) 5. (2) high, in high spirits -- (happy and excited and energetic) 6. gamey, gamy, high -- ((used of the smell of meat) smelling spoiled or tainted) 7. high, mellow -- (slightly and pleasantly intoxicated from alcohol or a drug (especially marijuana)) Overview of adv high The adv high has 4 senses (first 2 from tagged texts) 1. (9) high, high up -- (at a great altitude; "he climbed high on the ladder") 2. (2) high -- (in or to a high position, amount, or degree; "prices have gone up far too high") 3. high, richly, luxuriously -- (in a rich manner; "he lives high") 4. high -- (far up toward the source; "he lives high up the river") --- WordNet end ---