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kwic search for high out of >500 occurrences
636281 occurrences (No.11 in the rank) during 5 years in the PubMed. [no cache]
500 found
18) Intracerebral hemorrhage (ICH) in patients with oral anticoagulation therapy is an increasingly prevalent problem in large part due to the aging population and the increased use of anticoagulants for patients at high risk of thrombosis.
* Intracerebral hemorrhage in patients receiving oral anticoagulation therapy.
- Intracerebral hemorrhage (ICH) in patients with oral anticoagulation therapy is an increasingly prevalent problem in large part due to the aging population and the increased use of anticoagulants for patients at high risk of thrombosis. Warfarin has been virtually the only outpatient anticoagulant choice until fairly recently. The development of subcutaneously injected heparinoids, and more recently, of direct thrombin inhibitors, has made the treatment and prognostication of ICH in anticoagulated patients more difficult. In this review, we will review the current state of diagnosis, prognostication, and treatment for patients with this often-devastating type of bleeding. We will focus on warfarin therapy, because the preponderance of evidence comes from studies of warfarin treatment. Where there is evidence, we will contrast warfarin with some of the newer treatment modalities. We review the evidence of the 4 major reversal agents for warfarin, vitamin K, prothrombin complex concentrates, activated factor VII, and fresh frozen plasma as well as rational treatment choices. We offer possible treatments for the newer anticoagulants based on the limited evidence available. Finally, we review recommendations from the major societies and studies that support early and aggressive therapies in intensive care units with dedicated neurological specialists.
=>1.高いところにある, 高い, 高さが〜の, 高貴な, 高く, 高額の, 興奮状態の, 2.高い所, 高水準
Overview of noun high
The noun high has 7 senses (first 1 from tagged texts)
1. (5) high -- (a lofty level or position or degree; "summer temperatures reached an all-time high")
2. high -- (an air mass of higher than normal pressure; "the east coast benefits from a Bermuda
high")
3. high -- (a state of sustained elation; "I'm on a permanent high these days")
4. high -- (a state of altered consciousness induced by alcohol or narcotics; "they took drugs to
get a high on")
5. high, heights -- (a high place; "they stood on high and observed the countryside"; "he doesn't
like heights")
6. senior high school, senior high, high, highschool, high school -- (a public secondary school
usually including grades 9 through 12; "he goes to the neighborhood highschool")
7. high gear, high -- (a forward gear with a gear ratio that gives the greatest vehicle velocity for
a given engine speed)
Overview of adj high
The adj high has 7 senses (first 5 from tagged texts)
1. (134) high -- (greater than normal in degree or intensity or amount; "a high temperature"; "a
high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high";
"he has a high opinion of himself")
2. (51) high -- ((literal meaning) being at or having a relatively great or specific elevation or
upward extension (sometimes used in combinations like `knee-high'); "a high mountain"; "high
ceilings"; "high buildings"; "a high forehead"; "a high incline"; "a foot high")
3. (10) eminent, high -- (standing above others in quality or position; "people in high places";
"the high priest"; "eminent members of the community")
4. (7) high, high-pitched -- (used of sounds and voices; high in pitch or frequency)
5. (2) high, in high spirits -- (happy and excited and energetic)
6. gamey, gamy, high -- ((used of the smell of meat) smelling spoiled or tainted)
7. high, mellow -- (slightly and pleasantly intoxicated from alcohol or a drug (especially
marijuana))
Overview of adv high
The adv high has 4 senses (first 2 from tagged texts)
1. (9) high, high up -- (at a great altitude; "he climbed high on the ladder")
2. (2) high -- (in or to a high position, amount, or degree; "prices have gone up far too high")
3. high, richly, luxuriously -- (in a rich manner; "he lives high")
4. high -- (far up toward the source; "he lives high up the river")
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