ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for high out of >500 occurrences
636281 occurrences (No.11 in the rank) during 5 years in the PubMed. [no cache] 500 found
32) Compared with the low-risk group, the odds ratio for medium-low-, medium-high-, and high-risk group was 1.83 (95% CI: 1.23-2.72), 2.61 (95% CI: 1.79-3.80), and 3.05 (95% CI: 2.08-4.46), respectively (P for trend<0.001).
--- ABSTRACT ---
PMID:24038406 DOI:10.1002/mc.22073
2015 Molecular carcinogenesis
* Genetic variations in base excision repair pathway and risk of bladder cancer: a case-control study in the United States.
- Base excision repair (BER) is one of the major cellular DNA repair pathways that repairs small isolated foci of DNA damage including reduced or oxidized single bases or fragments and small, non-bulky adducts. Genetic variations in BER genes may affect DNA repair capacity and increase susceptibility to bladder cancer. In a case-control study of 801 bladder cancer patients and 801 matched controls, we evaluated the associations of 167 single nucleotide polymorphisms (SNPs) from 19 genes of the BER pathway with the risk of bladder cancer. In individual SNP analysis, 13 SNPs in 10 BER pathway genes were significantly associated with bladder cancer risk. The most significant SNP was rs2029167 in the SMUG1 gene. The homozygous variant GG genotype was associated with a 1.42-fold increased risk of bladder cancer (95% confidence interval [CI], 1.11-1.82, P=0.005). Cumulative effect analysis showed joint effects of increased risk of bladder cancer with increasing number of unfavorable genotypes in patients. Classification and regression tree analysis further revealed high-order gene-gene interactions and categorized the study subjects into low-, medium-low-, medium-high-, and high-risk groups. Compared with the low-risk group, the odds ratio for medium-low-, medium-high-, and high-risk group was 1.83 (95% CI: 1.23-2.72), 2.61 (95% CI: 1.79-3.80), and 3.05 (95% CI: 2.08-4.46), respectively (P for trend<0.001). Our results suggest that genetic variations in BER pathway genes modulate the risk of bladder cancer individually and jointly.
--- ABSTRACT END ---
[
right
kwic]
[frequency of next (right) word to high]
(1)18 risk (19)4 gamma (37)2 AT (55)2 importance
(2)14 and (20)4 group (38)2 N/L (56)2 index
(3)12 prevalence (21)4 patient (39)2 PbB (57)2 inter-specific
(4)10 levels (22)4 rate (40)2 accuracy (58)2 internal
(5)9 level (23)4 shear (41)2 age (59)2 job
(6)9 school (24)3 blood (42)2 alcohol (60)2 mass
(7)8 *null* (25)3 concentration (43)2 areas (61)2 population
(8)7 proportion (26)3 density (44)2 birth (62)2 positive
(9)6 in (27)3 dose (45)2 caries (63)2 production
(10)6 lipoprotein (28)3 efficiency (46)2 chemotherapy (64)2 profile
(11)6 liquid (29)3 frequency (47)2 correlation (65)2 relative
(12)6 mortality (30)3 genetic (48)2 dental (66)2 reliability
(13)5 as (31)3 groups (49)2 diet (67)2 resistance
(14)5 autism (32)3 incidence (50)2 exposure (68)2 risks'
(15)5 degree (33)3 patients (51)2 expression (69)2 specificity,
(16)4 concentrations (34)3 rates (52)2 frequencies (70)2 technologies
(17)4 doses (35)3 ulnar (53)2 heart (71)2 tumours
(18)4 for (36)2 ASD (54)2 hydrostatic (72)2 variability

add keyword

--- WordNet output for high --- =>1.高いところにある, 高い, 高さが〜の, 高貴な, 高く, 高額の, 興奮状態の, 2.高い所, 高水準 Overview of noun high The noun high has 7 senses (first 1 from tagged texts) 1. (5) high -- (a lofty level or position or degree; "summer temperatures reached an all-time high") 2. high -- (an air mass of higher than normal pressure; "the east coast benefits from a Bermuda high") 3. high -- (a state of sustained elation; "I'm on a permanent high these days") 4. high -- (a state of altered consciousness induced by alcohol or narcotics; "they took drugs to get a high on") 5. high, heights -- (a high place; "they stood on high and observed the countryside"; "he doesn't like heights") 6. senior high school, senior high, high, highschool, high school -- (a public secondary school usually including grades 9 through 12; "he goes to the neighborhood highschool") 7. high gear, high -- (a forward gear with a gear ratio that gives the greatest vehicle velocity for a given engine speed) Overview of adj high The adj high has 7 senses (first 5 from tagged texts) 1. (134) high -- (greater than normal in degree or intensity or amount; "a high temperature"; "a high price"; "the high point of his career"; "high risks"; "has high hopes"; "the river is high"; "he has a high opinion of himself") 2. (51) high -- ((literal meaning) being at or having a relatively great or specific elevation or upward extension (sometimes used in combinations like `knee-high'); "a high mountain"; "high ceilings"; "high buildings"; "a high forehead"; "a high incline"; "a foot high") 3. (10) eminent, high -- (standing above others in quality or position; "people in high places"; "the high priest"; "eminent members of the community") 4. (7) high, high-pitched -- (used of sounds and voices; high in pitch or frequency) 5. (2) high, in high spirits -- (happy and excited and energetic) 6. gamey, gamy, high -- ((used of the smell of meat) smelling spoiled or tainted) 7. high, mellow -- (slightly and pleasantly intoxicated from alcohol or a drug (especially marijuana)) Overview of adv high The adv high has 4 senses (first 2 from tagged texts) 1. (9) high, high up -- (at a great altitude; "he climbed high on the ladder") 2. (2) high -- (in or to a high position, amount, or degree; "prices have gone up far too high") 3. high, richly, luxuriously -- (in a rich manner; "he lives high") 4. high -- (far up toward the source; "he lives high up the river") --- WordNet end ---