312) On linear mixed model analysis, the subjects in the intervention group demonstrated higher mean Hb levels (13.01 vs 12.32 g/dL; P < .0001) and higher adherence to iron therapy (93% vs 60%; P < .0001). |
PMID:23666832 DOI:10.1177/1010539513486176 |
2015 Asia-Pacific journal of public health |
* A community-based cluster randomized controlled trial of "directly observed home-based daily iron therapy" in lowering prevalence of anemia in rural women and adolescent girls. |
- In a community-based cluster randomized controlled trial, we randomly assigned clusters of anemic women and adolescent girls to either "directly observed home-based daily iron therapy" (DOHBIT; n = 524 in 16 villages) or unsupervised self-treatment at home (n = 535 in 16 villages) for a period of 90 days. Those in the DOHBIT group, when compared with those in the unsupervised self-treatment group, had significantly lower relative risk (RR) of anemia (16.8% vs 35.3%, RR = 0.47 [95% confidence interval (CI) = 0.33-0.65]; P < .0001), higher hemoglobin (Hb) rise of ≥2 g/dL (70.2% vs 42.2%, RR = 1.56 [95% CI = 1.31-1.87]; P <.0001), and nonsignificant trend for lower side effects (3.5% vs 6.7%, RR = 0.49 [95% CI = 0.22-1.08; P < .08) on intention-to-treat analyses. On linear mixed model analysis, the subjects in the intervention group demonstrated higher mean Hb levels (13.01 vs 12.32 g/dL; P < .0001) and higher adherence to iron therapy (93% vs 60%; P < .0001). DOHBIT is effective in lowering the prevalence of anemia in rural women and adolescent girls. |
(1)69 in | (17)3 body | (33)2 by | (49)2 infant |
(2)63 than | (18)3 fatalism | (34)2 concentrations | (50)2 initial |
(3)21 levels | (19)3 likelihood | (35)2 coverage | (51)2 mean |
(4)17 risk | (20)3 odds | (36)2 degree | (52)2 order |
(5)10 level | (21)3 on | (37)2 different | (53)2 physiological |
(6)9 among | (22)3 quality | (38)2 dose | (54)2 probability |
(7)8 for | (23)2 (odds | (39)2 doses | (55)2 quantity |
(8)6 rates | (24)2 *null* | (40)2 drug | (56)2 rate |
(9)5 cell | (25)2 AT | (41)2 during | (57)2 relative |
(10)5 potency | (26)2 MTBS | (42)2 education | (58)2 revision |
(11)5 scores | (27)2 RDW | (43)2 education, | (59)2 sensitivity |
(12)4 compared | (28)2 abstinence | (44)2 expectations | (60)2 stress |
(13)4 number | (29)2 adjusted | (45)2 expression | (61)2 to |
(14)4 prevalence | (30)2 amount | (46)2 frequency | (62)2 total |
(15)3 (P | (31)2 birth | (47)2 incidence | (63)2 values |
(16)3 amounts | (32)2 blood | (48)2 individual |
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