2015 Journal of tissue engineering and regenerative medicine
* Research with parthenogenetic stem cells will help decide whether a safer clinical use is possible.
- The derivation and use of parthenogenetic stem cells (pESCs) are envisaged as a reliable alternative to conventional embryonic stem cells. Similar to embryonic stem cells in their proliferation, expression of pluripotency markers and capacity to multilineage differentiation, pESCs are at a lower risk of immune rejection within stem cell-based therapeutics. Moreover, pESCs represent an important model system to study the effect of paternally imprinted genes on cell differentiation. However, currently available information about the genetic and epigenetic behaviour of pESCs is limited. Thus, a detailed look at the biology of parthenogenetic (PG) embryos and PG-derived cell lines would allow gaining insight into the full potential of pESC in biotechnology. In this commentary article we review some features related to the biology of PG embryos and pESCs. In addition, novel traits on bovine pESCs (bpESCs) are discussed.
=>重要な, 有力な, 重大な, 大切な
Overview of adj important
The adj important has 5 senses (first 4 from tagged texts)
1. (146) important, of import -- (of great significance or value; "important people"; "the important
questions of the day")
2. (4) significant, important -- (important in effect or meaning; "a significant change in tax
laws"; "a significant change in the Constitution"; "a significant contribution"; "significant
details"; "statistically significant")
3. (2) crucial, important -- (of extreme importance; vital to the resolution of a crisis; "a crucial
moment in his career"; "a crucial election"; "a crucial issue for women")
4. (1) authoritative, important -- (having authority or ascendancy or influence; "an important
official"; "the captain's authoritative manner")
5. important -- (having or suggesting a consciousness of high position; "recited the decree with an
important air"; "took long important strides in the direction of his office")
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