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611425 occurrences (No.13 in the rank) during 5 years in the PubMed. [cache]

166) Abnormalities in fetal growth, including increased incidence of both large and small for gestational age babies, suggest placental dysfunction.

--- ABSTRACT ---

PMID:33958235 DOI:10.1016/j.placenta.2021.04.005

2021 Placenta

* Placental structural abnormalities in gestational diabetes and when they develop: A scoping review.

- Gestational diabetes mellitus (GDM) is defined as diabetes with onset or first recognition during gestation. It is a common complication of pregnancy that has become more prevalent over the past few decades. Abnormalities in fetal growth, including increased incidence of both large and small for gestational age babies, suggest placental dysfunction. The major goal of this scoping review is to determine what is known about abnormalities in placentas delivered from GDM pregnancies, and how early in gestation these abnormalities arise. A secondary goal is to review to what extent other selected factors, in particular obesity, have been found to influence or modify the reported effects of GDM on placental development, and whether these are considered in the study of GDM placentas. PubMed and Scopus databases were searched using the key terms: "gestational diabetes AND (woman OR human) AND placenta AND (ultrasound OR ultrastructure OR imaging OR histology OR pathology). Studies of gross morphology and histoarchitecture in placentas delivered from GDM pregnancies consistently report increased placental size, villous immaturity and a range of vascular lesions when compared to uncomplicated pregnancies. In contrast, a small number of ultrasound studies have examined placental development in GDM pregnancies in the second, and especially, the first trimester. Relatively few studies have analyzed interactions with maternal BMI, but these do suggest that it may play a role in placental abnormalities. Further examination of placental development early in pregnancy is needed to understand when it becomes disrupted in GDM, as a first step to identifying the underlying causes.

--- ABSTRACT END ---

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(1)53 risk	(17)4 significantly	(33)2 CYP2B6	(50)2 likelihood
(2)32 the	(18)4 survival	(34)2 DNA	(51)2 mental
(3)19 in	(19)3 and	(35)2 ROS	(52)2 neutrophil
(4)11 levels	(20)3 at	(36)2 T	(53)2 odds
(5)8 by	(21)3 during	(38)2 airway	(54)2 patients'
(6)8 over	(22)3 exposure	(39)2 appetite,	(55)2 placental
(7)6 null	(23)3 focus	(40)2 approximately	(56)2 probability
(8)6 awareness	(24)3 for	(41)2 body	(57)2 rate
(9)6 expression	(25)3 from	(42)2 cell	(58)2 research
(10)6 or	(26)3 mortality	(43)2 demands	(59)2 resolution
(11)5 after	(27)3 sensitivity	(44)2 depressive	(60)2 retropalatal
(12)5 use	(28)3 severity	(45)2 detection	(61)2 substantially
(13)4 incidence	(29)3 signal	(46)2 health	(62)2 their
(14)4 prevalence	(30)3 time	(47)2 intracranial	(63)2 total
(15)4 production	(31)3 to	(48)2 intratumoral	(64)2 uptake
(16)4 serum	(32)3 vaccine	(49)2 lifespan	(65)2 virus

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--- WordNet output for increased --- =>力の増加 Overview of verb increase The verb increase has 2 senses (first 2 from tagged texts) 1. (86) increase -- (become bigger or greater in amount; "The amount of work increased") 2. (61) increase -- (make bigger or more; "The boss finally increased her salary"; "The university increased the number of students it admitted") Overview of adj increased The adj increased has 1 sense (first 1 from tagged texts) 1. (30) increased -- (made greater in size or amount or degree) --- WordNet end ---