ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for increased out of >500 occurrences
611425 occurrences (No.13 in the rank) during 5 years in the PubMed. [cache]
223) In addition, the number of hypoxic and inflammatory cells was found to be increased at particular time points.
--- ABSTRACT ---
PMID:24028468 DOI:10.1111/iwj.12143
2015 International wound journal
* Vessel transformation in chronic wounds under topical negative pressure therapy: an immunohistochemical analysis.
- The underlying physiological mechanism of topical negative pressure (TNP) therapy is not yet completely understood. This prospective clinical study aims to clarify a potential influence of TNP therapy on vessel proliferation and hypoxia in chronic wounds. TNP was applied on chronic wounds of 16 patients (-125 mmHg) to prepare them for a plastic-surgical reconstruction using free or pedicled flaps. Tissue biopsies were taken from the wound edge and wound bed at different time points. All samples were stained with haematoxylin and eosin, hypoxia-induced factor-1α and endothelial cell markers (CD31 and CD34) for the immunohistological analysis of inflammation, hypoxia and vessel proliferation. Between day 5 and day 8 of treatment, a considerable increase in blood vessel density could be observed, reaching a maximum of approximately 200% in contrast to the vessel density prior to treatment. In addition, the number of hypoxic and inflammatory cells was found to be increased at particular time points. This study demonstrates a stimulating effect on vessel proliferation under TNP treatment. TNP appears to support (neo-) angiogenesis and transformation of chronic non-healing wounds in a physiological wound healing process when combined with surgical debridement. This effect underlines the positive influence of TNP in the treatment of chronic wounds as shown by various clinical reports.
--- ABSTRACT END ---
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(1)36 the (14)5 to (27)2 RDW (40)2 likelihood
(2)34 in (15)4 after (28)2 awareness (41)2 maternal
(3)27 risk (16)4 as (29)2 bone (42)2 morbidity
(4)21 *null* (17)3 activity (30)2 but (43)2 number
(5)20 with (18)3 among (31)2 compared (44)2 over
(6)16 by (19)3 at (32)2 concentrations (45)2 pre-stimulus
(7)15 significantly (20)3 cell (33)2 drug (46)2 production
(8)6 and (21)3 level (34)2 during (47)2 rapidly
(9)6 expression (22)3 levels (35)2 fax (48)2 use
(10)6 from (23)3 physical (36)2 functional (49)2 vascular
(11)5 activation (24)3 sensitivity (37)2 hepatic
(12)5 odds (25)2 MI (38)2 if
(13)5 serum (26)2 Math1 (39)2 interest

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--- WordNet output for increased --- =>力の増加 Overview of verb increase The verb increase has 2 senses (first 2 from tagged texts) 1. (86) increase -- (become bigger or greater in amount; "The amount of work increased") 2. (61) increase -- (make bigger or more; "The boss finally increased her salary"; "The university increased the number of students it admitted") Overview of adj increased The adj increased has 1 sense (first 1 from tagged texts) 1. (30) increased -- (made greater in size or amount or degree) --- WordNet end ---