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ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
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486851 occurrences (No.30 in the rank) during 5 years in the PubMed. [no cache] 500 found
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486851 occurrences (No.30 in the rank) during 5 years in the PubMed. [no cache] 500 found
| 153) However, recent progress in CRC molecular therapies may provide new insight into the treatment of this disease. |
| PMID:24420815 DOI:10.1002/ijc.28722 |
| 2015 International journal of cancer |
| * Molecular therapy of colorectal cancer: progress and future directions. |
| - Colorectal cancer (CRC) remains one of the most common types of cancer and leading causes of cancer death worldwide. Although the introduction of cytotoxic drugs such as oxaliplatin, irinotecan and fluorouracil has improved the treatment of advanced CRC, the individual response to chemoradiotherapy varies tremendously from one patient to another. However, recent progress in CRC molecular therapies may provide new insight into the treatment of this disease. Currently, components of the EGFR, VEGF, Wnt and NF-kB pathways are the most important targets for CRC therapy. This review chronicles the development of molecular CRC therapies over the past few decades. We also provide an update on the current progress of research concerning the molecular pathways leading to CRC and discuss the possible implications for CRC therapy. |
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