ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for new out of >500 occurrences
486851 occurrences (No.30 in the rank) during 5 years in the PubMed. [no cache] 500 found
20) New bone formation in the former defect site did not differ between the two groups (BCP: 49.2%; β-TCP: 52.4%).
--- ABSTRACT ---
PMID:24439994 DOI:10.1016/j.aanat.2013.12.001
2015 Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
* Comparative study of biphasic calcium phosphate with beta-tricalcium phosphate in rat cranial defects--A molecular-biological and histological study.
- The aim of this study was to evaluate the in vivo biocompatibility of a biphasic calcium phosphate (BCP) bone graft substitute consisting of 60% hydroxyapatite and 40% β-tricalcium phosphate (β-TCP) in comparison to a pure β-TCP of identical shape and porosity. The materials were evaluated using an established rat cranial defect model in 24 animals. One bone defect with a diameter of 5mm was created per animal. The defects were filled with either BCP or β-TCP and left to heal for 4 weeks. Twelve samples (6 per material) were processed for histological evaluation and immunohistochemistry. The remaining 12 samples were processed for mRNA expression analysis. No signs of inflammation or adverse material reactions were detected. New bone formation in the former defect site did not differ between the two groups (BCP: 49.2%; β-TCP: 52.4%). Osteoblast-like and TRAP-positive osteoclast-like cells were found at the surface of the bone graft substitute granules. The β-TCP group showed significantly higher mRNA levels for the bone resorption marker Acp5 and osteogenic differentiation marker Runx2. The expression of IGF1, IGF2, VEGF, Phex, Alpl, Col1, Col2, Bglap and MMP8 did not differ between the groups. The in vivo biocompatibility of BCP is to a large part identical to those of TCP. Within the limitation of the animal model, the implantation study shows that BCP can be used as bone graft substitute, due to the fact that the material integrates into tissue, remains stable in the implantation bed and serves as an osteoconductive scaffold.
--- ABSTRACT END ---
[
right
kwic]
[frequency of next (right) word to new]
(1)19 Zealand (19)4 targets (37)2 Zealand, (55)2 important
(2)13 bone (20)3 DP (38)2 avenues (56)2 innovations
(3)12 approach (21)3 York, (39)2 biomarkers (57)2 instrument
(4)11 and (22)3 approaches (40)2 blood (58)2 methodologies
(5)10 method (23)3 concepts (41)2 case (59)2 methods
(6)9 insights (24)3 information (42)2 cases (60)2 parameters
(7)7 York (25)3 insight (43)2 challenges (61)2 policy
(8)7 therapeutic (26)3 light (44)2 co-processed (62)2 public
(9)5 data (27)3 media (45)2 compound (63)2 risk
(10)5 molecular (28)3 molecules (46)2 concept (64)2 strategies
(11)5 species (29)3 regulation (47)2 diagnostic (65)2 strategy
(12)4 World (30)3 research (48)2 driver (66)2 subspecies
(13)4 class (31)3 technique (49)2 drug (67)2 training
(14)4 clinical (32)3 treatment (50)2 endemic (68)2 type
(15)4 discoveries (33)2 Graves' (51)2 evidence (69)2 way
(16)4 generation (34)2 HIV (52)2 findings
(17)4 measure (35)2 South (53)2 genetic
(18)4 model (36)2 York/Japan (54)2 health

add keyword

--- WordNet output for new --- =>新発見の, 新しい, 現代的な, 新参の Overview of adj new The adj new has 11 senses (first 5 from tagged texts) 1. (310) new -- (not of long duration; having just (or relatively recently) come into being or been made or acquired or discovered; "a new law"; "new cars"; "a new comet"; "a new friend"; "a new year"; "the New World") 2. (36) fresh, new, novel -- (original and of a kind not seen before; "the computer produced a completely novel proof of a well-known theorem") 3. (11) raw, new -- (lacking training or experience; "the new men were eager to fight"; "raw recruits") 4. (5) new, unexampled -- (having no previous example or precedent or parallel; "a time of unexampled prosperity") 5. (3) new -- (other than the former one(s); different; "they now have a new leaders"; "my new car is four years old but has only 15,000 miles on it"; "ready to take a new direction") 6. new -- (unaffected by use or exposure; "it looks like new") 7. newfangled, new -- ((of a new kind or fashion) gratuitously new; "newfangled ideas"; "she buys all these new-fangled machines and never uses them") 8. New -- (in use after medieval times; "New Eqyptian was the language of the 18th to 21st dynasties") 9. Modern, New -- (used of a living language; being the current stage in its development; "Modern English"; "New Hebrew is Israeli Hebrew") 10. new, young -- ((of crops) harvested at an early stage of development; before complete maturity; "new potatoes"; "young corn") 11. new -- (unfamiliar; "new experiences"; "experiences new to him"; "errors of someone new to the job") Overview of adv new The adv new has 1 sense (first 1 from tagged texts) 1. (1) newly, freshly, fresh, new -- (very recently; "they are newly married"; "newly raised objections"; "a newly arranged hairdo"; "grass new washed by the rain"; "a freshly cleaned floor"; "we are fresh out of tomatoes") --- WordNet end ---