ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
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kwic search for observed out of >500 occurrences
392826 occurrences (No.45 in the rank) during 5 years in the PubMed. [no cache]
500 found
296) Significant improvements from baseline in Psoriasis Area Severity Index were observed with etanercept therapy at all time points over 24 weeks (p<0.001) independent of PsA history.
* Cardiometabolic profile, clinical features, quality of life and treatment outcomes in patients with moderate-to-severe psoriasis and psoriatic arthritis.
- Cardiometabolic, clinical and quality-of-life (QoL) measures were assessed before and after etanercept treatment in patients who had moderate-to-severe plaque psoriasis with and without psoriatic arthritis (PsA) in the PRISTINE trial. Adult patients were randomized to receive etanercept 50 mg once weekly or twice weekly double-blind for 12 weeks; all patients subsequently received etanercept 50 mg once weekly open-label through week 24. Metabolic syndrome was identified in 44 and 41% of patients with and without PsA, elevated blood pressure in 73 and 56% (p<0.05) and diabetes in 21 and 9% (p<0.01), respectively. Significant improvements from baseline in Psoriasis Area Severity Index were observed with etanercept therapy at all time points over 24 weeks (p<0.001) independent of PsA history. At baseline, patients with PsA had worse QoL than patients without PsA. After 24 weeks of etanercept, both groups had significant improvement from baseline in QoL, but the PsA group had greater improvement than that without PsA. Cardiovascular comorbidities were common in psoriasis patients with and without PsA, suggesting that clinicians need to be attentive to cardiometabolic parameters in this population. Worse QoL was demonstrated in PsA versus psoriasis alone. Regardless of patients' PsA status, treatment with etanercept significantly improved skin symptoms and QoL measures.
Overview of verb observe
The verb observe has 9 senses (first 8 from tagged texts)
1. (39) detect, observe, find, discover, notice -- (discover or determine the existence, presence,
or fact of; "She detected high levels of lead in her drinking water"; "We found traces of lead in
the paint")
2. (17) note, observe, mention, remark -- (make mention of; "She observed that his presentation took
up too much time"; "They noted that it was a fine day to go sailing")
3. (12) note, take note, observe -- (observe with care or pay close attention to; "Take note of this
chemical reaction")
4. (10) observe -- (watch attentively; "Please observe the reaction of these two chemicals")
5. (4) respect, honor, honour, abide by, observe -- (show respect towards; "honor your parents!")
6. (3) observe, celebrate, keep -- (behave as expected during of holidays or rites; "Keep the
commandments"; "celebrate Christmas"; "Observe Yom Kippur")
7. (2) watch, observe, follow, watch over, keep an eye on -- (follow with the eyes or the mind;
"Keep an eye on the baby, please!"; "The world is watching Sarajevo"; "She followed the men with the
binoculars")
8. (1) observe, keep, maintain -- (stick to correctly or closely; "The pianist kept time with the
metronome"; "keep count"; "I cannot keep track of all my employees")
9. observe, keep -- (conform one's action or practice to; "keep appointments"; "she never keeps her
promises"; "We kept to the original conditions of the contract")
Overview of adj observed
The adj observed has 1 sense (first 1 from tagged texts)
1. (7) ascertained, discovered, observed -- (discovered or determined by scientific observation;
"variation in the ascertained flux depends on a number of factors"; "the discovered behavior norms";
"discovered differences in achievement"; "no explanation for the observed phenomena")
--- WordNet end ---