* Association of Nonacute Opioid Use and Cardiovascular Diseases: A Scoping Review of the Literature.
- BACKGROUND In this scoping review, we identified and reviewed 23 original articles from the PubMed database that investigated the relationship between nonacute opioid use (NOU) and cardiovascular outcomes. METHODS AND RESULTS We defined NOU to include both long-term opioid therapy and opioid use disorder. We summarized the association between NOU and 5 classes of cardiovascular disease, including infective endocarditis, coronary heart disease (including myocardial infarction), congestive heart failure, cardiac arrythmia (including cardiac arrest), and stroke. The most commonly studied outcomes were coronary heart disease and infective endocarditis. There was generally consistent evidence of a positive association between community prevalence of injection drug use (with opioids being the most commonly injected type of drug) and community prevalence of infective endocarditis, and between (primarily medically indicated) NOU and myocardial infarction. There was less consensus about the relationship between NOU and congestive heart failure, cardiac arrhythmia, and stroke. CONCLUSIONS There is a dearth of high-quality evidence on the relationship between NOU and cardiovascular disease. Innovative approaches to the assessment of opioid exposure over extended periods of time will be required to address this need.
=>1.超えて, 一面に, 移って, 始めから終わりまで, 終わって, を支配して, の間, しながら, 倒れて, の上に,
を覆って, を越えて, の向こう側に, より多く, 2.もう一度, 繰り返して
Overview of noun over
The noun over has 1 sense (no senses from tagged texts)
1. over -- ((cricket) the division of play during which six balls are bowled at the batsman by one
player from the other team from the same end of the pitch)
Overview of adj over
The adj over has 1 sense (first 1 from tagged texts)
1. (21) complete, concluded, ended, over, all over, terminated -- (having come or been brought to a
conclusion; "the harvesting was complete"; "the affair is over, ended, finished"; "the abruptly
terminated interview")
Overview of adv over
The adv over has 5 senses (first 3 from tagged texts)
1. (23) over -- (at or to a point across intervening space etc.; "come over and see us some time";
"over there")
2. (2) over -- (throughout an area; "he is known the world over")
3. (1) over, o'er -- (throughout a period of time; "stay over the weekend")
4. over -- (beyond the top or upper surface or edge; forward from an upright position; "a roof that
hangs over";)
5. all over, over -- (over the entire area; "the wallpaper was covered all over with flowers"; "she
ached all over"; "everything was dusted over with a fine layer of soot")
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