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545945 occurrences (No.21 in the rank) during 5 years in the PubMed. [cache]
202) In the present study, the effects of xenoestrogen 4-nonylphenol (4-NP) and 17β-estradiol (E2) on the synthesis of vitellogenin (VTG) in immature male yellowfin seabream (Acanthoparus latus) were assessed to determine the potential use of this species as a biological model for studying endocrine disrupters in the Musa estuary in southern seawaters of Iran.
* Induction of vitellogenin synthesis in immature male yellowfin seabream (Acanthopagrus latus) exposed to 4-nonylphenol and 17β-estradiol.
- In the present study, the effects of xenoestrogen 4-nonylphenol (4-NP) and 17β-estradiol (E2) on the synthesis of vitellogenin (VTG) in immature male yellowfin seabream (Acanthoparus latus) were assessed to determine the potential use of this species as a biological model for studying endocrine disrupters in the Musa estuary in southern seawaters of Iran. A total number of 104 fish were injected by 10, 50, 100, 150 and 200 µg g(-) (1) week(-) (1) of 4-NP and 2 µg g(-) (1) week(-) (1) of E2, and their blood plasma was obtained for biochemical analysis on days 0, 7 and 14. The hepatosomatic index (HSI) of each fish was also recorded at each sampling time. The results showed that 4-NP significantly induced VTG synthesis in A. latus, which was detected by gel electrophoresis as two major protein bands (∼210 and 191 KDa). The induction of VTG was also determined indirectly by measuring the alkali-labile phosphate, total plasma calcium and protein. All of these VTG indicators significantly increased in the plasma of 4-NP- and E2-treated fish. Meanwhile, a significant dose-dependent increase was observed in HSI, indicating the activation of hepatic VTG production in 4-NP- and E2-injected fish. Furthermore, the plasma alanine aminotransferase and aspartate aminotransferase concentrations significantly increased in 4-NP-treated fish, presumably reflecting a situation of hepatic tissue damage due to 4-NP toxicity. Based on the results, it is suggested that A. latus could be used successfully as a model species for future studies of endocrine disrupting contaminants in the Musa estuary.
=>可能性のある, 可能な, 潜在力のある, 位置の, 電位の, 潜在的な, ポテンシャル, 可能性, 電位
Overview of noun potential
The noun potential has 2 senses (first 1 from tagged texts)
1. (10) potential, potentiality, potency -- (the inherent capacity for coming into being)
2. electric potential, potential, potential difference, potential drop, voltage -- (the difference
in electrical charge between two points in a circuit expressed in volts)
Overview of adj potential
The adj potential has 2 senses (first 2 from tagged texts)
1. (7) potential, possible -- (existing in possibility; "a potential problem"; "possible uses of
nuclear power")
2. (6) likely, potential -- (expected to become or be; in prospect; "potential clients")
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