ELIZA

return kwic search for protein out of >500 occurrences
536761 occurrences (No.22 in the rank) during 5 years in the PubMed. [no cache] 500 found

89) Exercise-related benefits include (a) increased mitochondrial biogenesis/enzyme activity, (b) reconditioning of immune/inflammatory pathways, (c) decreased endoplasmic reticulum stress, (d) modulation of gene expression, (e) increased protein synthesis and cytoskeletal remodeling, and (f) decreased muscle fibrosis and non-muscle area infiltrates.

--- ABSTRACT ---

PMID:33793075 DOI:10.1111/1756-185X.14104

2021 International journal of rheumatic diseases

* The pathophysiological effects of exercise in the management of idiopathic inflammatory myopathies: A scoping review.

- Idiopathic inflammatory myopathy (IIM) is a term used for a heterogeneous group of diseases characterized by severe muscle weakness. In addition to pharmacological treatment options, non-pharmacological methods such as exercising are essential for proper management of myositis. The present article aimed to provide an insight into the potential pathophysiological mechanisms underlying exercise-related benefits in myositis. A systematic search was performed on PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar using the following keywords and their combinations: "idiopathic inflammatory myopathy", "inflammatory myopathy", "myositis", "polymyositis", "dermatomyositis", "inclusion body myositis", and "exercise". Current literature indicates that exercising has impact on both immune and non-immune pathways in patients with IIM. Exercise-related benefits include (a) increased mitochondrial biogenesis/enzyme activity, (b) reconditioning of immune/inflammatory pathways, (c) decreased endoplasmic reticulum stress, (d) modulation of gene expression, (e) increased protein synthesis and cytoskeletal remodeling, and (f) decreased muscle fibrosis and non-muscle area infiltrates. With its certain benefits, exercise stands as a precious non-pharmacological treatment option for patients with IIM.

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[frequency of next (right) word to protein]

(1)24 expression	(18)4 binding	(35)3 interaction	(52)2 folding
(2)20 and	(19)4 components	(36)3 involved	(53)2 gene
(3)18 null	(20)4 from	(37)3 modifications	(54)2 kinases
(4)15 kinase	(21)4 function	(38)3 with	(55)2 kinases,
(5)11 levels	(22)4 import	(39)2 (BCRP),	(56)2 level
(6)9 synthesis	(23)4 interactions	(40)2 (CRP)	(57)2 levels,
(7)8 1	(24)4 of	(41)2 adducts	(58)2 mass
(8)8 abundance	(25)4 or	(42)2 aggregation	(59)2 may
(9)8 that	(26)4 to	(43)2 approach	(60)2 networks
(10)7 receptors	(27)3 (BCRP)	(44)2 as	(61)2 per
(11)6 receptor	(28)3 9	(45)2 binding,	(62)2 quantification
(12)5 3	(29)3 a	(46)2 bound	(63)2 response
(13)5 in	(30)3 activation	(47)2 coupling	(64)2 restriction
(14)5 is	(31)3 biomarkers	(48)2 diet	(65)2 structure
(15)5 pool	(32)3 coupled	(49)2 during	(66)2 synthesis,
(16)5 was	(33)3 degradation	(50)2 expression,	(67)2 targets
(17)4 2	(34)3 genes	(51)2 family

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--- WordNet output for protein --- =>タンパク質, 蛋白質, たん白質 Overview of noun protein The noun protein has 1 sense (first 1 from tagged texts) 1. (23) protein -- (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein") --- WordNet end ---