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return kwic search for provide out of >500 occurrences
325270 occurrences (No.61 in the rank) during 5 years in the PubMed. [cache]

33) We provide a direct comparison of various in vitro interneuron derivation methods to determine the homogeneity achieved.

--- ABSTRACT ---

PMID:34506726 DOI:10.1016/j.stemcr.2021.08.006

2021 Stem cell reports

* Defining the nature of human pluripotent stem cell-derived interneurons via single-cell analysis.

- The specification of inhibitory neurons has been described for the mouse and human brain, and many studies have shown that pluripotent stem cells (PSCs) can be used to create interneurons in vitro. It is unclear whether in vitro methods to produce human interneurons generate all the subtypes found in brain, and how similar in vitro and in vivo interneurons are. We applied single-nuclei and single-cell transcriptomics to model interneuron development from human cortex and interneurons derived from PSCs. We provide a direct comparison of various in vitro interneuron derivation methods to determine the homogeneity achieved. We find that PSC-derived interneurons capture stages of development prior to mid-gestation, and represent a minority of potential subtypes found in brain. Comparison with those found in fetal or adult brain highlighted decreased expression of synapse-related genes. These analyses highlight the potential to tailor the method of generation to drive formation of particular subtypes.

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[frequency of next (right) word to provide]

(1)125 a	(12)7 insight	(23)3 sufficient	(34)2 patients
(2)63 an	(13)7 more	(24)3 support	(35)2 protection
(3)15 evidence	(14)6 guidance	(25)2 adequate	(36)2 readers
(4)13 the	(15)6 information	(26)2 care	(37)2 reasonable
(5)12 new	(16)6 some	(27)2 critical	(38)2 reliable
(6)11 recommendations	(17)5 novel	(28)2 detailed	(39)2 robust
(7)9 insights	(18)4 better	(29)2 direct	(40)2 strong
(8)9 valuable	(19)4 opportunities	(30)2 greater	(41)2 suggestions
(9)7 additional	(20)4 useful	(31)2 hypotheses	(42)2 treatment
(10)7 further	(21)3 practical	(32)2 key
(11)7 important	(22)3 researchers	(33)2 mechanistic

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--- WordNet output for provide --- =>供給する, 与える, 規定する, 条件とする, 準備する, 用意する, 扶養する, 援助する Overview of verb provide The verb provide has 7 senses (first 4 from tagged texts) 1. (270) supply, provide, render, furnish -- (give something useful or necessary to; "We provided the room with an electrical heater") 2. (25) provide, supply, ply, cater -- (give what is desired or needed, especially support, food or sustenance; "The hostess provided lunch for all the guests") 3. (14) provide -- (determine (what is to happen in certain contingencies), especially by including a proviso condition or stipulation; "The will provides that each child should receive half of the money"; "The Constitution provides for the right to free speech") 4. (2) put up, provide, offer -- (mount or put up; "put up a good fight"; "offer resistance") 5. leave, allow for, allow, provide -- (make a possibility or provide opportunity for; permit to be attainable or cause to remain; "This leaves no room for improvement"; "The evidence allows only one conclusion"; "allow for mistakes"; "leave lots of time for the trip"; "This procedure provides for lots of leeway") 6. provide, bring home the bacon -- (supply means of subsistence; earn a living; "He provides for his large family by working three jobs"; "Women nowadays not only take care of the household but also bring home the bacon") 7. provide -- (take measures in preparation for; "provide for the proper care of the passengers on the cruise ship") --- WordNet end ---