ELIZA

return kwic search for response out of >500 occurrences
343831 occurrences (No.54 in the rank) during 5 years in the PubMed. [cache]

163) Most of these molecules are mediators of immune response.

--- ABSTRACT ---

PMID:24397626 DOI:10.1111/jfd.12195

2015 Journal of fish diseases

* Experimental infection of brown-marbled grouper, Epinephelus fuscoguttatus (Forskal), with Vibrio parahaemolyticus identifies parvalbumin beta-2 subunit I, alpha-2-macroglobulin, nattectin and immunoglobulin light chain, differentially expressed in resistant grouper.

- The mechanisms through which brown-marbled grouper accomplishes resistance to infection, particularly against Vibrios, are not yet fully understood. In this study, brown-marbled grouper fingerlings were experimentally infected with Vibrio parahaemolyticus, to identify disease resistance grouper, and the serum proteome profiles were compared between resistant and susceptible candidates, via two-dimensional gel electrophoresis (2-DE). The results showed that putative parvalbumin beta-2 subunit I, alpha-2-macroglobulin, nattectin and immunoglobulin light chain proteins were among proteins that significantly overexpressed in the resistant fish as compared to the susceptible group of fish, whereas apolipoprotein E and immunoglobulin light chain proteins were observed to be differentially overexpressed in the susceptible fish. Further analysis by peptide sequencing revealed that the immunoglobulin light chain proteins identified in the resistant and susceptible groups differed in amino acid composition. Taken together, the results demonstrated for the first time that putative parvalbumin beta-2 subunit I, alpha-2-macroglobulin, nattectin and immunoglobulin light chain are among important proteins participating to effect disease resistance mechanism in fish and were overexpressed to function collectively to resist V. parahaemolyticus infection. Most of these molecules are mediators of immune response.

--- ABSTRACT END ---

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[frequency of next (right) word to response]

(1)146 to	(14)4 proteins	(27)3 time	(40)2 following
(2)32 null	(15)4 rates	(28)3 times	(41)2 from
(3)31 and	(16)4 that	(29)3 which	(42)2 including
(4)22 of	(17)4 the	(30)2 (ABR)	(43)2 latency
(5)21 rate	(18)3 at	(31)2 (DDR)	(44)2 mediated
(6)14 was	(19)3 during	(32)2 (UPR)	(45)2 or
(7)13 in	(20)3 elements	(33)2 after	(46)2 rate)
(8)8 selection	(21)3 models	(34)2 are	(47)2 rates,
(9)7 surface	(22)3 options	(35)2 boundaries	(48)2 such
(10)6 data	(23)3 properties	(36)2 delays	(49)2 theory
(11)6 is	(24)3 strategies	(37)2 effects	(50)2 validity
(12)4 for	(25)3 style	(38)2 element	(51)2 were
(13)4 patterns	(26)3 suppression	(39)2 evaluation

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--- WordNet output for response --- =>反応, 応答, 返答, 返報, 反響, 答唱句 Overview of noun response The noun response has 7 senses (first 5 from tagged texts) 1. (11) response -- (a result; "this situation developed in response to events in Africa") 2. (11) reaction, response -- (a bodily process occurring due to the effect of some antecedent stimulus or agent; "a bad reaction to the medicine"; "his responses have slowed with age") 3. (6) answer, reply, response -- (a statement (either spoken or written) that is made to reply to a question or request or criticism or accusation; "I waited several days for his answer"; "he wrote replies to several of his critics") 4. (4) reception, response -- (the manner in which something is greeted; "she did not expect the cold reception she received from her superiors") 5. (1) response -- (a phrase recited or sung by the congregation following a versicle by the priest or minister) 6. reply, response -- (the speech act of continuing a conversational exchange; "he growled his reply") 7. response -- (the manner in which an electrical or mechanical device responds to an input signal or a range of input signals) --- WordNet end ---