ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -

return kwic search for significantly out of >500 occurrences
583352 occurrences (No.14 in the rank) during 5 years in the PubMed. [no cache] 500 found
28) The concentration of conjugated dienes was significantly higher in both subgroups, whereas the activity of malate dehydrogenase was significantly higher only in the group with higher exposure.
--- ABSTRACT ---
PMID:23833244 DOI:10.1177/0748233713483204
2015 Toxicology and industrial health
* The metabolism of carbohydrates and lipid peroxidation in lead-exposed workers.
- The present study was undertaken to estimate the effect of occupational exposure to lead on the blood concentration of glucose and several enzymes involved in glycolysis, the citric acid cycle, and the pentose phosphate pathway. To estimate the degree of lipid peroxidation, the concentrations of conjugated dienes were determined. The examined group included 145 healthy male employees of lead-zinc works. Taking into account the mean blood lead levels, the examined group was divided into two subgroups. The control group was composed of 36 healthy male administrative workers. The markers of lead exposure were significantly elevated in both subgroups when compared with the controls. There were no significant changes in fasting glucose concentration and fructose-1,6-bisphosphate aldolase activity in the study population. The concentration of conjugated dienes was significantly higher in both subgroups, whereas the activity of malate dehydrogenase was significantly higher only in the group with higher exposure. The activities of lactate dehydrogenase and sorbitol dehydrogenase were significantly decreased in the examined subgroups. The activity of glucose-6-phosphate dehydrogenase decreased significantly in the group with higher exposure and could be the cause of the elevated concentrations of conjugated dienes. It is possible to conclude that lead interferes with carbohydrate metabolism, but compensatory mechanisms seem to be efficient, as glucose homeostasis in lead-exposed workers was not disturbed.
--- ABSTRACT END ---
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[frequency of next (right) word to significantly]
(1)88 higher (13)8 improved (25)3 (P<0.05) (39)2 impaired
(2)43 lower (14)6 correlated (27)3 affect (40)2 increases
(3)39 increased (15)6 elevated (28)3 better (41)2 induced
(4)35 reduced (16)6 fewer (29)3 increase (42)2 larger
(5)32 associated (17)6 less (30)3 worse (43)2 predicted
(6)17 decreased (18)5 enhanced (31)2 (P (44)2 reduce
(7)13 in (19)5 inhibited (32)2 (p (45)2 shorter
(8)13 more (20)4 affected (34)2 altered (46)2 smaller
(9)10 greater (21)4 attenuated (35)2 by (47)2 suppressed
(10)10 related (22)4 between (36)2 compared (48)2 to
(11)9 *null* (23)4 from (37)2 decreased,
(12)9 different (24)4 the (38)2 differed

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--- WordNet output for significantly --- =>きわめて, 意味深く, 意味ありげに Overview of adv significantly The adv significantly has 3 senses (first 2 from tagged texts) 1. (6) significantly -- (in a statistically significant way; "the two groups differed significantly") 2. (3) significantly -- (in a significant manner; "our budget will be significantly affected by these new cuts") 3. importantly, significantly -- (in an important way or to an important degree; "more importantly, Weber held that the manifold meaning attached to the event by the social scientist could alter his definition of the concrete event itself") --- WordNet end ---