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ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
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532339 occurrences (No.23 in the rank) during 5 years in the PubMed. [no cache] 500 found
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532339 occurrences (No.23 in the rank) during 5 years in the PubMed. [no cache] 500 found
| 301) Despite the availability of methods for assessing power in longitudinal studies with missing data, the impact on power of the magnitude and distribution of missing data in the study population remain poorly understood. |
| PMID:22357710 DOI:10.1177/0962280212437452 |
| 2015 Statistical methods in medical research |
| * A comparison of power analysis methods for evaluating effects of a predictor on slopes in longitudinal designs with missing data. |
| - In many longitudinal studies, evaluating the effect of a binary or continuous predictor variable on the rate of change of the outcome, i.e. slope, is often of primary interest. Sample size determination of these studies, however, is complicated by the expectation that missing data will occur due to missed visits, early drop out, and staggered entry. Despite the availability of methods for assessing power in longitudinal studies with missing data, the impact on power of the magnitude and distribution of missing data in the study population remain poorly understood. As a result, simple but erroneous alterations of the sample size formulae for complete/balanced data are commonly applied. These 'naive' approaches include the average sum of squares and average number of subjects methods. The goal of this article is to explore in greater detail the effect of missing data on study power and compare the performance of naive sample size methods to a correct maximum likelihood-based method using both mathematical and simulation-based approaches. Two different longitudinal aging studies are used to illustrate the methods. |
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--- WordNet output for studies ---