* Subtle differences in autonomic symptoms in people diagnosed with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders.
- The hypermobile Ehlers-Danlos syndrome (hEDS) GENE study is a multicenter, cohort study with the goal to identify genes associated with hypermobile EDS. Of the 148 people enrolled in the hEDS GENE study, 98 meet the 2017 hEDS criteria, 27 have a hypermobility spectrum disorder (HSD) and 23 are asymptomatic family members. More than 80% of participants are female with an average age of 41 years. Each participant has completed seven questionnaires to quantify disease-related symptomatology. People with hypermobility experience a variety of physical and somatic symptoms, especially in the areas of fatigue, kinesiophobia, gastrointestinal, and autonomic function. These cause a significant decrease in health-related quality of life. The frequency and severity of most symptoms were indistinguishable between participants with hEDS and HSD; however, there were significant differences in autonomic symptoms. Less than 20% of participants had autoantibodies known to be associated with dysautonomia. Subtle symptomatic differences in people meeting the 2017 diagnostic criteria suggest focusing further etiologic studies on autonomic pathways.
=>〜しようと提案する, を提案する, 示唆する, 暗示する, 提案する
Overview of verb suggest
The verb suggest has 5 senses (first 5 from tagged texts)
1. (57) propose, suggest, advise -- (make a proposal, declare a plan for something; "the senator
proposed to abolish the sales tax")
2. (21) hint, suggest -- (drop a hint; intimate by a hint)
3. (19) suggest, intimate -- (imply as a possibility; "The evidence suggests a need for more
clarification")
4. (14) indicate, suggest -- (suggest the necessity of an intervention; in medicine; "Tetracycline
is indicated in such cases")
5. (12) suggest, evoke, paint a picture -- (call to mind; "this remark evoked sadness")
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