2015 Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
* Presence of antiheparin/platelet factor 4 immunoglobulin g is associated with poor prognosis in patients with suspected disseminated intravascular coagulation.
- The underlying inflammatory or infectious condition in disseminated intravascular coagulation (DIC) may stimulate the formation of antiheparin/platelet factor 4 (PF4) antibody, and the resulting antibody may affect the clinical course of DIC. We investigated the prognosis of antiheparin/PF4 antibodies in patients with suspected DIC. We measured heparin/PF4 immunoglobulin G (IgG) and total antibody levels using an automated chemiluminescence system in 118 patients with DIC. Of the 118 patients, 13 (11.0%) patients were positive for total antiheparin/PF4, and 6 (5.1%) patients were positive for antiheparin/PF4 IgG. These 13 patients were negative for platelet-activating antibody and had low-heparin-induced thrombocytopenia probability scores. Patients with antiheparin/PF4 IgG were older and had lower antithrombin levels than patients without antiheparin/PF4 IgG. Patients with antiheparin/PF4 IgG had a higher risk of mortality than those without antiheparin/PF4 IgG. The presence of antiheparin/PF4 IgG in old age or low antithrombin level patients with DIC with old age or low antithrombin level suggests a poor prognosis.
=>制度組織体系的方式, システム, 組織, 整然とした手順, (思想などの)体系, 体制
Overview of noun system
The noun system has 9 senses (first 8 from tagged texts)
1. (43) system -- (instrumentality that combines interrelated interacting artifacts designed to work
as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small
computer")
2. (23) system, scheme -- (a group of independent but interrelated elements comprising a unified
whole; "a vast system of production and distribution and consumption keep the country going")
3. (14) system -- ((physical chemistry) a sample of matter in which substances in different phases
are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system
generating hydrogen peroxide")
4. (10) system, system of rules -- (a complex of methods or rules governing behavior; "they have to
operate under a system they oppose"; "that language has a complex system for indicating gender")
5. (8) arrangement, organization, organisation, system -- (an organized structure for arranging or
classifying; "he changed the arrangement of the topics"; "the facts were familiar but it was in the
organization of them that he was original"; "he tried to understand their system of classification")
6. (7) system -- (a group of physiologically or anatomically related organs or parts; "the body has
a system of organs for digestion")
7. (6) system -- (a procedure or process for obtaining an objective; "they had to devise a system
that did not depend on cooperation")
8. (1) system -- (the living body considered as made up of interdependent components forming a
unified whole; "exercise helped him get the alcohol out of his system")
9. organization, organisation, system -- (an ordered manner; orderliness by virtue of being
methodical and well organized; "his compulsive organization was not an endearing quality"; "we can't
do it unless we establish some system around here")
--- WordNet end ---