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return kwic search for system out of >500 occurrences
331253 occurrences (No.58 in the rank) during 5 years in the PubMed. [no cache] 500 found

273) We employed as model cell system the human neuroblastoma cell line SHSY5Y, which is a well-established system for studying neuronal differentiation.

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PMID:23065911 DOI:10.1002/term.1618

2015 Journal of tissue engineering and regenerative medicine

* Neuronal growth and differentiation on biodegradable membranes.

- Semipermeable polymeric membranes with appropriate morphological, physicochemical and transport properties are relevant to inducing neural regeneration. We developed novel biodegradable membranes to support neuronal differentiation. In particular, we developed chitosan, polycaprolactone and polyurethane flat membranes and a biosynthetic blend between polycaprolactone and polyurethane by phase-inversion techniques. The biodegradable membranes were characterized in order to evaluate their morphological, physicochemical, mechanical and degradation properties. We investigated the efficacy of these different membranes to promote the adhesion and differentiation of neuronal cells. We employed as model cell system the human neuroblastoma cell line SHSY5Y, which is a well-established system for studying neuronal differentiation. The investigation of viability and specific neuronal marker expression allowed assessment that the correct neuronal differentiation and the formation of neuronal network had taken place in vitro in the cells seeded on different biodegradable membranes. Overall, this study provides evidence that neural cell responses depend on the nature of the biodegradable polymer used to form the membranes, as well as on the dissolution, hydrophilic and, above all, mechanical membrane properties. PCL-PU membranes exhibit mechanical properties that improve neurite outgrowth and the expression of specific neuronal markers.

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[frequency of next (right) word to system]

(1)88 null	(12)6 by	(23)3 (ANS)	(34)2 diseases
(2)30 and	(13)6 has	(24)3 (CNS)	(35)2 including
(3)19 is	(14)5 are	(25)3 a	(36)2 involvement
(4)18 of	(15)5 might	(26)3 after	(37)2 known
(5)18 was	(16)5 the	(27)3 as	(38)2 on
(6)17 in	(17)4 Adhesive	(28)3 based	(39)2 one
(7)16 that	(18)4 can	(29)3 development	(40)2 plays
(8)15 for	(19)4 have	(30)3 we	(41)2 related
(9)13 to	(20)4 may	(31)2 (GIS)	(42)2 results
(10)8 which	(21)4 using	(32)2 containing	(43)2 used
(11)7 with	(22)4 were	(33)2 demonstrated

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--- WordNet output for system --- =>制度組織体系的方式, システム, 組織, 整然とした手順, (思想などの)体系, 体制 Overview of noun system The noun system has 9 senses (first 8 from tagged texts) 1. (43) system -- (instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer") 2. (23) system, scheme -- (a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going") 3. (14) system -- ((physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide") 4. (10) system, system of rules -- (a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender") 5. (8) arrangement, organization, organisation, system -- (an organized structure for arranging or classifying; "he changed the arrangement of the topics"; "the facts were familiar but it was in the organization of them that he was original"; "he tried to understand their system of classification") 6. (7) system -- (a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion") 7. (6) system -- (a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation") 8. (1) system -- (the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system") 9. organization, organisation, system -- (an ordered manner; orderliness by virtue of being methodical and well organized; "his compulsive organization was not an endearing quality"; "we can't do it unless we establish some system around here") --- WordNet end ---