2015 Journal of the renin-angiotensin-aldosterone system : JRAAS
* The renin-angiotensin system meets the hallmarks of cancer.
- The hallmarks of cancer are described as the distinctive and complementary capacities that cells must acquire during the multistep development of becoming a cancer cell that allow them to survive, proliferate and disseminate. The renin-angiotensin system (RAS) was first discovered and extensively studied in the physiological regulation of systemic arterial pressure. RAS signalling increases cell proliferation in malignancy by directly affecting tumour and stromal cells and by indirectly modulating the growth of vascular cells during angiogenesis. We aim to describe and give a general view of how the RAS is involved in several hallmarks of cancer and how this could open a window to several interesting treatments.
=>制度組織体系的方式, システム, 組織, 整然とした手順, (思想などの)体系, 体制
Overview of noun system
The noun system has 9 senses (first 8 from tagged texts)
1. (43) system -- (instrumentality that combines interrelated interacting artifacts designed to work
as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small
computer")
2. (23) system, scheme -- (a group of independent but interrelated elements comprising a unified
whole; "a vast system of production and distribution and consumption keep the country going")
3. (14) system -- ((physical chemistry) a sample of matter in which substances in different phases
are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system
generating hydrogen peroxide")
4. (10) system, system of rules -- (a complex of methods or rules governing behavior; "they have to
operate under a system they oppose"; "that language has a complex system for indicating gender")
5. (8) arrangement, organization, organisation, system -- (an organized structure for arranging or
classifying; "he changed the arrangement of the topics"; "the facts were familiar but it was in the
organization of them that he was original"; "he tried to understand their system of classification")
6. (7) system -- (a group of physiologically or anatomically related organs or parts; "the body has
a system of organs for digestion")
7. (6) system -- (a procedure or process for obtaining an objective; "they had to devise a system
that did not depend on cooperation")
8. (1) system -- (the living body considered as made up of interdependent components forming a
unified whole; "exercise helped him get the alcohol out of his system")
9. organization, organisation, system -- (an ordered manner; orderliness by virtue of being
methodical and well organized; "his compulsive organization was not an endearing quality"; "we can't
do it unless we establish some system around here")
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