ELIZA

return kwic search for there out of >500 occurrences
271290 occurrences (No.96 in the rank) during 5 years in the PubMed. [cache]

444) There has been a growing interest in the potential for plasticity-inducing pharmacological interventions to enhance post-stroke recovery.

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PMID:31346698 DOI:10.1007/s00415-019-09480-0

2021 Journal of neurology

* Selective serotonin reuptake inhibitors for functional recovery after stroke: similarities with the critical period and the role of experience-dependent plasticity.

- There has been a growing interest in the potential for plasticity-inducing pharmacological interventions to enhance post-stroke recovery. One group of drugs that continues to garner a great deal of attention in this regard is a class of antidepressants called the selective serotonin reuptake inhibitors. Here we propose a model for the mechanism by which these drugs may enhance plasticity after ischemic brain injury. First, we review the research in animal models demonstrating how selective serotonin reuptake inhibitors reopen the critical period for ocular dominance plasticity in adulthood. We then compare this period of heightened plasticity to the cellular and biochemical milieu of perilesional tissue after an ischemic event in the adult brain. We argue that selective serotonin reuptake inhibitors administered acutely after an ischemic stroke alter excitatory-inhibitory balance in perilesional tissue and reinstate a type of plasticity reminiscent of the critical period in development. Finally, we discuss opportunities for future research in this area in both the preclinical and clinical realms.

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(1)242 is	(3)68 was	(5)26 has	(7)5 remains
(2)84 are	(4)49 were	(6)9 have	(8)3 appears

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--- WordNet output for there --- =>1.その場所で, そこに(で), そこへ, 2.〜がある, その場所で Overview of noun there The noun there has 1 sense (no senses from tagged texts) 1. there -- (a location other than here; that place; "you can take it from there") Overview of adv there The adv there has 3 senses (first 3 from tagged texts) 1. (181) there, at that place, in that location -- (in or at that place; "they have lived there for years"; "it's not there"; "that man there") 2. (6) there, in that respect, on that point -- (in that matter; "I agree with you there") 3. (2) there, thither -- (to or toward that place; away from the speaker; "go there around noon!") --- WordNet end ---