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kwic search for time out of >500 occurrences
357929 occurrences (No.51 in the rank) during 5 years in the PubMed. [no cache] 500 found
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357929 occurrences (No.51 in the rank) during 5 years in the PubMed. [no cache] 500 found
| 342) As in previous studies, we found that predictable in-time targets were better detected than unpredictable out-of-time targets. |
| PMID:24152544 DOI:10.1093/cercor/bht297 |
| 2015 Cerebral cortex (New York, N.Y. : 1991) |
| * TMS over V5 disrupts motion prediction. |
| - Given the vast amount of sensory information the brain has to deal with, predicting some of this information based on the current context is a resource-efficient strategy. The framework of predictive coding states that higher-level brain areas generate a predictive model to be communicated via feedback connections to early sensory areas. Here, we directly tested the necessity of a higher-level visual area, V5, in this predictive processing in the context of an apparent motion paradigm. We flashed targets on the apparent motion trace in-time or out-of-time with the predicted illusory motion token. As in previous studies, we found that predictable in-time targets were better detected than unpredictable out-of-time targets. However, when we applied functional magnetic resonance imaging-guided, double-pulse transcranial magnetic stimulation (TMS) over left V5 at 13-53 ms before target onset, the detection advantage of in-time targets was eliminated; this was not the case when TMS was applied over the vertex. Our results are causal evidence that V5 is necessary for a prediction effect, which has been shown to modulate V1 activity (Alink et al. 2010). Thus, our findings suggest that information processing between V5 and V1 is crucial for visual motion prediction, providing experimental support for the predictive coding framework. |
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--- WordNet output for time ---