ELIZA

return kwic search for total out of >500 occurrences
296134 occurrences (No.80 in the rank) during 5 years in the PubMed. [cache]

360) Molecular analysis included 144 tests in total.

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PMID:24102599 DOI:10.3109/19401736.2013.840594

2015 Mitochondrial DNA

* Mitochondrial DNA polymorphism in genes encoding ND1, COI and CYTB in canine malignant cancers.

- The aim of the study was to identify DNA changes in mitochondrial gene fragments: NADH dehydrogenase subunit 1 (ND1), cytochrome c oxidase subunit I (COI) and cytochrome b (CYTB) in tumor tissue, normal tissue and blood, and to define their association with the tumor type in dogs. Molecular analysis included 144 tests in total. A functional effect of the non-synonymous protein coding SNP was predicted. The presence of polymorphisms in all tested gene fragments in individual tissues of dogs was observed. Heteroplasmic changes were found in ND1 and CYTB in epithelioma glandulae sebacei and in CYTB in lymphoma centroblasticum. The results of in silico analysis show the impact of these alleles (COI: 507, ND1: 450, 216, CYTB: 748) on the functioning of proteins and thus their potential role in carcinogenesis. The possible harmful effects of changes in polypeptides in positions T193N, V98M, V118M and H196P were evaluated. It seems that polymorphisms occurring in cells can have a negative impact on functioning of proteins. This promotes disorders of the energy level in cells.

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(1)187 of	(14)3 adhesive	(27)2 BGP	(40)2 organic
(2)21 length	(15)3 annual	(28)2 DNA,	(41)2 oxidant
(3)13 number	(16)3 delivered	(29)2 activity	(42)2 pleural
(4)7 antioxidant	(17)3 knee	(30)2 arch	(43)2 protein,
(5)7 protein	(18)3 length,	(31)2 biomass	(44)2 repetitions
(6)5 body	(19)3 optical	(32)2 collagen	(45)2 scores
(7)5 cholesterol	(20)3 or	(33)2 daily	(46)2 snack
(8)5 dose	(21)3 parenteral	(34)2 dietary	(47)2 soluble
(9)5 score	(22)3 polyphenols	(35)2 exercise	(48)2 stress
(10)4 HG	(23)3 population	(36)2 genome	(49)2 tumor
(11)4 amount	(24)3 sample	(37)2 health-care	(50)2 volume
(12)4 and	(25)3 suspended	(38)2 islet
(13)4 cell	(26)2 248	(39)2 mitochondrial

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--- WordNet output for total --- =>1.(車が)全壊する, 全損する, 2.全体の, 全ての, 総計の, 総体の, 全くの, 完全な, 総力の, 3.総額, 総計, 全体の, (車が)全壊する, 合計(する), なる Overview of noun total The noun total has 2 senses (first 2 from tagged texts) 1. (13) sum, total, totality, aggregate -- (the whole amount) 2. (6) sum, amount, total -- (a quantity obtained by the addition of a group of numbers) Overview of verb total The verb total has 3 senses (first 2 from tagged texts) 1. (16) total, number, add up, come, amount -- (add up in number or quantity; "The bills amounted to $2,000"; "The bill came to $2,000") 2. (2) total, tot, tot up, sum, sum up, summate, tote up, add, add together, tally, add up -- (determine the sum of; "Add all the people in this town to those of the neighboring town") 3. total -- (damage beyond the point of repair; "My son totaled our new car"; "the rock star totals his guitar at every concert") Overview of adj total The adj total has 2 senses (first 2 from tagged texts) 1. (31) entire, full, total -- (constituting the full quantity or extent; complete; "an entire town devastated by an earthquake"; "gave full attention"; "a total failure") 2. (2) full, total -- (complete in extent or degree and in every particular; "a full game"; "a total eclipse"; "a total disaster") --- WordNet end ---