ELIZA

return kwic search for treatment out of >500 occurrences
677804 occurrences (No.8 in the rank) during 5 years in the PubMed. [no cache] 500 found

206) This therapy may represent an alternative treatment for eradicating resistant strains.

--- ABSTRACT ---

PMID:23748800 DOI:10.1007/s10103-013-1354-x

2015 Lasers in medical science

* Antimicrobial photodynamic therapy against pathogenic bacterial suspensions and biofilms using chloro-aluminum phthalocyanine encapsulated in nanoemulsions.

- Antimicrobial photodynamic therapy represents an alternative method of killing resistant pathogens. Efforts have been made to develop delivery systems for hydrophobic drugs to improve the photokilling. This study evaluated the photodynamic effect of chloro-aluminum phthalocyanine (ClAlPc) encapsulated in nanoemulsions (NE) on methicillin-susceptible and methicillin-resistant Staphylococcus aureus suspensions and biofilms. Suspensions and biofilms were treated with different delivery systems containing ClAlPc. After the pre-incubation period, the drug was washed-out and irradiation was performed with LED source (660 ± 3 nm). Negative control samples were not exposed to ClAlPc or light. For the suspensions, colonies were counted (colony-forming units per milliliter (CFU/mL)). The metabolic activity of S. aureus suspensions and biofilms were evaluated by the XTT assay. The efficiency was dependent on the delivery system, superficial load and light dose. Cationic NE-ClAlPc and free-ClAlPc caused photokilling of the both strains of S. aureus. For biofilms, cationic NE-ClAlPc reduced cell metabolism by 80 and 73% of susceptible and resistant strains, respectively. Although anionic NE-ClAlPc caused a significant CFU/ml reduction for MSSA and MRSA, it was not capable of reducing MRSA biofilm metabolism. This therapy may represent an alternative treatment for eradicating resistant strains.

--- ABSTRACT END ---

[
right
kwic]

[frequency of next (right) word to treatment]

(1)101 of	(14)4 showed	(27)3 the	(40)2 leads
(2)53 null	(15)4 were	(28)3 to	(41)2 led
(3)38 with	(16)3 as	(29)3 without	(42)2 may
(4)29 for	(17)3 by	(30)2 after	(43)2 program
(5)23 and	(18)3 cycle	(31)2 also	(44)2 protocols
(6)11 in	(19)3 group	(32)2 are	(45)2 response
(7)9 was	(20)3 modalities	(33)2 can	(46)2 schizophrenia
(8)6 groups	(21)3 on	(34)2 concentration	(47)2 seems
(9)6 options	(22)3 option	(35)2 cycles	(48)2 significantly
(10)5 or	(23)3 outcomes	(36)2 effects	(49)2 strategies
(11)4 allocation	(24)3 period	(37)2 group,
(12)4 completion	(25)3 plants	(38)2 induced
(13)4 effect	(26)3 success	(39)2 is

add keyword

--- WordNet output for treatment --- =>1.取り扱い, 扱い, 治療, 待遇, 処理, 処置, 2.台本, シナリオ Overview of noun treatment The noun treatment has 4 senses (first 4 from tagged texts) 1. (28) treatment, intervention -- (care provided to improve a situation (especially medical procedures or applications that are intended to relieve illness or injury)) 2. (25) treatment, handling -- (the management of someone or something; "the handling of prisoners"; "the treatment of water sewage"; "the right to equal treatment in the criminal justice system") 3. (4) treatment -- (a manner of dealing with something artistically; "his treatment of space borrows from Italian architecture") 4. (2) discussion, treatment, discourse -- (an extended communication (often interactive) dealing with some particular topic; "the book contains an excellent discussion of modal logic"; "his treatment of the race question is badly biased") --- WordNet end ---