* Vinorelbine rescue therapy for dogs with primary urinary bladder carcinoma.
- The goal of this study was to evaluate the anti-tumour activity and toxicoses of vinorelbine as a palliative rescue therapy for dogs with primary urinary bladder carcinoma. Thirteen dogs refractory to prior chemotherapeutics and one dog naïve to chemotherapeutic treatment were enrolled. Vinorelbine (15 mg m(-2) IV) was administered intravenously along with concurrent oral anti-inflammatory drugs, if tolerated. A median of six doses of vinorelbine (range: 1-16) was administered. Two dogs (14%) had partial responses, and eight (57%) experienced stable disease. Subjective improvement in clinical signs was noted in 11 dogs (78%). Adverse events were mild and primarily haematological in nature. Median time to progression was 93 days (range: 20-239 days). Median survival time for all dogs was 187 days; median survival for 13 pre-treated dogs was 207 days. Vinorelbine may have utility in the management of canine primary urinary bladder carcinoma and should be evaluated in a prospective study.
=>1.取り扱い, 扱い, 治療, 待遇, 処理, 処置, 2.台本, シナリオ
Overview of noun treatment
The noun treatment has 4 senses (first 4 from tagged texts)
1. (28) treatment, intervention -- (care provided to improve a situation (especially medical
procedures or applications that are intended to relieve illness or injury))
2. (25) treatment, handling -- (the management of someone or something; "the handling of prisoners";
"the treatment of water sewage"; "the right to equal treatment in the criminal justice system")
3. (4) treatment -- (a manner of dealing with something artistically; "his treatment of space
borrows from Italian architecture")
4. (2) discussion, treatment, discourse -- (an extended communication (often interactive) dealing
with some particular topic; "the book contains an excellent discussion of modal logic"; "his
treatment of the race question is badly biased")
--- WordNet end ---
PubMed database: last updated on 2023-01-29 (c)sirasawa 2019