204) Capillary hemangioma is the most common benign tumor of eyelids and orbit in children. |
PMID:24074395 DOI:10.3109/08820538.2013.821505 |
2015 Seminars in ophthalmology |
* Managment of superficial infantile capillary hemangiomas with topical timolol maleate solution. |
- Capillary hemangioma is the most common benign tumor of eyelids and orbit in children. Recently, a topical beta blocker has been reported as an effective treatment for superficial capillary hemangiomas. We present a case report of two children having large capillary hemangiomas who responded well to topical treatment by 0.5% timolol maleate solution. After 12 months of treatment, the lesion has significantly reduced in size, thickness, and color in both cases. Thus, we conclude that long-term use of topical 0.5% timolol maleate solution is safe and effective in treating superficial capillary hemangiomas. |
(1)36 cells | (17)6 size | (33)3 lysis | (49)2 progression, |
(2)23 suppressor | (18)6 suppression | (34)3 onset | (50)2 recurred |
(3)22 progression | (19)6 tissue | (35)3 targeting | (51)2 recurrence |
(4)20 necrosis | (20)6 with | (36)3 to | (52)2 regression |
(5)19 *null* | (21)5 angiogenesis | (37)3 types | (53)2 response |
(6)17 growth | (22)5 initiating | (38)2 1 | (54)2 samples, |
(7)15 cell | (23)5 suppressive | (39)2 activity | (55)2 site |
(8)14 was | (24)5 volume | (40)2 burden | (56)2 size, |
(9)12 and | (25)4 model | (41)2 classification | (57)2 that |
(10)11 development | (26)4 sites | (42)2 composed | (58)2 the |
(11)11 in | (27)4 suppressors | (43)2 expression | (59)2 tissue, |
(12)11 of | (28)3 effects | (44)2 heterogeneity | (60)2 tissues |
(13)7 microenvironment | (29)3 excision | (45)2 invasion | (61)2 treatment |
(14)6 formation | (30)3 extension | (46)2 is | |
(15)6 promotion | (31)3 had | (47)2 metastasis | |
(16)6 samples | (32)3 local | (48)2 mice |
add keyword