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305909 occurrences (No.73 in the rank) during 5 years in the PubMed. [no cache] 500 found
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[frequency of next (right) word to tumor]
305909 occurrences (No.73 in the rank) during 5 years in the PubMed. [no cache] 500 found
| 213) A hallmark of cancer, this alteration is characterized by dysfunctional metabolic enzymes, changes in nutrient availability, tumor microenvironment and oncogenic mutations. |
| PMID:24125862 DOI:10.1016/j.canlet.2013.09.043 |
| 2015 Cancer letters |
| * Epigenetics and cancer metabolism. |
| - Cancer cells adapt their metabolism to support proliferation and survival. A hallmark of cancer, this alteration is characterized by dysfunctional metabolic enzymes, changes in nutrient availability, tumor microenvironment and oncogenic mutations. Metabolic rewiring in cancer is tightly connected to changes at the epigenetic level. Enzymes that mediate epigenetic status of cells catalyze posttranslational modifications of DNA and histones and influence metabolic gene expression. These enzymes require metabolites that are used as cofactors and substrates to carry out reactions. This interaction of epigenetics and metabolism constitutes a new avenue of cancer biology and could lead to new insights for the development of anti-cancer therapeutics. |
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| (5)19 *null* | (21)5 angiogenesis |
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(24)5 volume |
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(25)4 model |
(41)2 classification |
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(60)2 tissues |
| (13)7 microenvironment |
(29)3 excision |
(45)2 invasion |
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| (14)6 formation |
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| (15)6 promotion |
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--- WordNet output for tumor ---