ELIZA

return kwic search for tumor out of >500 occurrences
305909 occurrences (No.73 in the rank) during 5 years in the PubMed. [no cache] 500 found

224) In addition, none of the grafted hNSCs were bromodeoxyuridine positive in the monkey brain, indicating that hNSCs did not replicate in the NHP brain and did not cause tumor formation.

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PMID:24480401 DOI:10.3727/096368914X678526

2015 Cell transplantation

* Long-term survival and differentiation of human neural stem cells in nonhuman primate brain with no immunosuppression.

- Cellular fate of human neural stem cells (hNSCs) transplanted in the brain of nonhuman primates (NHPs) with no immunosuppression was determined at 22 and 24 months posttransplantation (PTx) regarding survival, differentiation, and tumorigenesis. Survival of hNSCs labeled with magnetic nanoparticles was successfully detected around injection sites in the brain at 22 months PTx by MRI. Histological examination of brain sections with H&E and Prussian blue staining at 24 months revealed that most of the grafted hNSCs were found located along the injection tract. Grafted hNSCs were found to differentiate into neurons at 24 months PTx. In addition, none of the grafted hNSCs were bromodeoxyuridine positive in the monkey brain, indicating that hNSCs did not replicate in the NHP brain and did not cause tumor formation. This study serves as a proof of principle and provides evidence that hNSCs transplanted in NHP brain could survive and differentiate into neurons in the absence of immunosuppression. It also serves as a preliminary study in our scheduled preclinical studies of hNSC transplantation in NHP stroke models.

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[frequency of next (right) word to tumor]

(1)36 cells	(17)6 size	(33)3 lysis	(49)2 progression,
(2)23 suppressor	(18)6 suppression	(34)3 onset	(50)2 recurred
(3)22 progression	(19)6 tissue	(35)3 targeting	(51)2 recurrence
(4)20 necrosis	(20)6 with	(36)3 to	(52)2 regression
(5)19 null	(21)5 angiogenesis	(37)3 types	(53)2 response
(6)17 growth	(22)5 initiating	(38)2 1	(54)2 samples,
(7)15 cell	(23)5 suppressive	(39)2 activity	(55)2 site
(8)14 was	(24)5 volume	(40)2 burden	(56)2 size,
(9)12 and	(25)4 model	(41)2 classification	(57)2 that
(10)11 development	(26)4 sites	(42)2 composed	(58)2 the
(11)11 in	(27)4 suppressors	(43)2 expression	(59)2 tissue,
(12)11 of	(28)3 effects	(44)2 heterogeneity	(60)2 tissues
(13)7 microenvironment	(29)3 excision	(45)2 invasion	(61)2 treatment
(14)6 formation	(30)3 extension	(46)2 is
(15)6 promotion	(31)3 had	(47)2 metastasis
(16)6 samples	(32)3 local	(48)2 mice

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--- WordNet output for tumor --- =>膨らみ, 出っ張り, 腫瘍 Overview of noun tumor The noun tumor has 1 sense (first 1 from tagged texts) 1. (18) tumor, tumour, neoplasm -- (an abnormal new mass of tissue that serves no purpose) --- WordNet end ---