kwic
under
under
right
off
ON
170
1
100
500
strict
ELIZA cgi-bash version rev. 1.90
- Medical English LInking keywords finder for the PubMed Zipped Archive (ELIZA) -
return
kwic search for under out of >500 occurrences
321496 occurrences (No.66 in the rank) during 5 years in the PubMed. [no cache] 500 found
--- ABSTRACT ---
--- ABSTRACT END ---
[frequency of next (right) word to under]
321496 occurrences (No.66 in the rank) during 5 years in the PubMed. [no cache] 500 found
| 170) Then, TR-HG was reversed to a fluid and the cell suspension injected into the PDDM and kept under static loading for 7 days. |
| PMID:23303720 DOI:10.1002/term.1667 |
| 2015 Journal of tissue engineering and regenerative medicine |
| * A papain-induced disc degeneration model for the assessment of thermo-reversible hydrogel-cells therapeutic approach. |
| - Nucleus pulposus (NP) regeneration by the application of injectable cell-embedded hydrogels is an appealing approach for tissue engineering. We investigated a thermo-reversible hydrogel (TR-HG), based on a modified polysaccharide with a thermo-reversible polyamide [poly(N-isopropylacrylamide), pNIPAM], which is made to behave as a liquid at room temperature and hardens at > 32 °C. In order to test the hydrogel, a papain-induced bovine caudal disc degeneration model (PDDM), creating a cavity in the NP, was employed. Human mesenchymal stem cells (hMSCs) or autologous bovine NP cells (bNPCs) were seeded in TR-HG; hMSCs were additionally preconditioned with rhGDF-5 for 7 days. Then, TR-HG was reversed to a fluid and the cell suspension injected into the PDDM and kept under static loading for 7 days. Experimental design was: (D1) fresh disc control + PBS injection; (D2) PDDM + PBS injection; (D3) PDDM + TR-HG (material control); (D4) PDDM + TR-HG + bNPCs; (D5) PDDM + TR-HG + hMSCs. Magnetic resonance imaging performed before and after loading, on days 9 and 16, allowed imaging of the hydrogel-filled PDDM and assessment of disc height and volume changes. In gel-injected discs the NP region showed a major drop in volume and disc height during culture under static load. The RT-PCR results of injected hMSCs showed significant upregulation of ACAN, COL2A1, VCAN and SOX9 during culture in the disc cavity, whereas the gene expression profile of NP cells remained unchanged. The cell viability of injected cells (NPCs or hMSCs) was maintained at over 86% in 3D culture and dropped to ~72% after organ culture. Our results underline the need for load-bearing hydrogels that are also cyto-compatible. |
[
right
kwic]
(1)95  the |
(18)4 these |
(35)2 axial |
(52)2 of |
| (2)13 different |
(19)3 high |
(36)2 censoring |
(53)2 optimal |
| (3)12 a |
(20)3 investigation |
(37)2 clinical |
(54)2 physiological |
| (4)9 general |
(21)3 light |
(38)2 consideration |
(55)2 pulsatile |
| (5)8 both |
(22)3 local |
(39)2 controlled |
(56)2 scanning |
| (6)8 which |
(23)3 mechanical |
(40)2 current |
(57)2 serum-free |
| (7)7 various |
(24)2 *null* | (41)2 evaluation |
(58)2 several |
| (8)6 conditions |
(25)2 12 |
(42)2 ex |
(59)2 simulated |
| (9)6 curve |
(26)2 15 |
(43)2 extreme |
(60)2 specific |
| (10)6 static |
(27)2 2 |
(44)2 four |
(61)2 steady-state |
| (11)5 and |
(28)2 CA |
(45)2 hypertensive |
(62)2 therapy |
| (12)4 5 |
(29)2 CT |
(46)2 hypoxia |
(63)2 this |
| (13)4 certain |
(30)2 H2O2-induced |
(47)2 hypoxic |
(64)2 time |
| (14)4 control |
(31)2 UV |
(48)2 inflammatory |
(65)2 treatment |
| (15)4 either |
(32)2 acute |
(49)2 laser |
(66)2 ultrasound |
| (16)4 in |
(33)2 additive |
(50)2 lateral |
(67)2 vertical |
| (17)4 normal |
(34)2 adverse |
(51)2 mortality |
(68)2 water |
add keyword
--- WordNet output for under ---